Calcium-binding EGF domain-containing protein (CBDP)Gene functionsToxoplasma gondiiSeveral calcium-binding proteins including calcium-dependent protein kinases play important roles in several facets of the intracellular infection cycle of the apicomplexan protozoan parasite Toxoplasma gondii. However, the role...
产品名称:Human Collagen and calcium-binding EGF domain-containing protein 1 (CCBE1) ELIS 产品型号:abx576671 产品展商:其它品牌 产品文档:无相关文档 简单介绍 Human Collagen and calcium-binding EGF domain-containing protein 1 (CCBE1) ELISA Kit ...
Rapid metabolic reprogramming mediated by the AMP-activated protein kinase during the lytic cycle of Toxoplasma gondii Yaqiong Li Zhipeng Niu Bang Shen Nature Communications (2023) Effect of deleting four Toxoplasma gondii calcium-binding EGF domain-containing proteins on parasite replication and virulen...
Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by th...
Our results revealed that complex formation between sTF and FVIIa during Ca 2+ titration is initiated upon Ca 2+ binding to EGF1, the domain containing the site of highest Ca 2+ affinity. Besides we showed that a Ca 2+-loaded Gla domain is required for an optimal association of all ...
Finally, EFhd2 becomes dephosphorylated after epidermal growth factor (EGF) stimulation of HeLa cells with the same kinetics as the actin binding protein gelsolin [42]. Taken together, these data demonstrate that EFhd2 is associated with the cytoskeleton but the exact connection is unknown at ...
(3) Zinc finger CCCH domain-containing protein 12D (ZC3H12D, p34, 312aa), probably a ribonuclease and possibly a tumour suppressor. (4) Alpha- and gamma-adaptin-binding protein p34 (315aa). (5) A rickettsial protein (300aa) belonging to the cation diffusion facilitator (CDF) transporter...
mircofibrillar-associated protein 5 POSTN: periostin LOXL1: lysyl oxidase-like 1 ITGBL1: osteoblast-specific cysteine-rich protein MEGF10: multiple EGF-like-domains 10 COL5A1: collagen, type V, alpha 1 COL6A2: collagen, type VI, alpha 2 LOX: lysyl oxidase PLAU: plasminogen activator, urokin...
5a). Several additional non-FDA-approved small molecules, Rhosin (inhibits the Rho-GEF binding domain), CK-666 (inhibitor of the Arp2/3 complex and actin assembly), and Golgicide A (inhibits Arf1-mediated actin organization) were similarly capable of completely preventing adhesions in our bead...
MFS pathophysiology. Using steered molecular dynamics (SMD) simulations, we demonstrate that cbEGF domain calcium binding decreases under mechanical stress (i.e. cbEGF domains are mechanosensitive). We further demonstrate the disulfide bonds in cbEGF domains uniquely orchestrate protein unfolding by ...