The calcium signal is mediated and controlled by many proteins in the cell, the majority of which belong to the EF-hand super-family of calcium-binding proteins. EF-hand proteins are classified into calcium signal sensors and modulators. The calcium modulators fine-tune the shape and duration ...
Secretagogin (SCGN) is a recently discovered calcium binding protein of the EF hand family, cloned from β cells of pancreatic island of Langerhans and endocrine cells of the gastrointestinal gland. SCGN characterizes some particular neuron groups in various regions of the nervous system and is ...
Helix-loop-helix fragments of EF-hand proteins are known to dimerize in solution, re-producing the characteristic structure of native protein domains [Shaw... J Wójcik,J Góral,K Paw?Owski,... - 《Biochemistry》 被引量: 76发表: 1997年 The S100 family of EF-hand calcium-binding proteins:...
S100 calcium binding protein A5 (S100A5) belongs to the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 family members are localized in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such...
To date, the EF-hand homolog family contains more than 160 different -modulated which have a broad range of functions. Among them, are the , the , the , the , the S-100 and the 9- and 28 kDa. The most striking feature of the EF-hand family is the ability to modulate the ...
Protein alignment revealed that NlSEF1 is homologous to a predicted multiple coagulation factor defi- ciency protein 2 (MCFD2) that belongs to the EF-hand 7 family (PF13499) and is characterized by a pair of EF-hand domains. In humans, MCFD2 is a soluble luminal protein and a part of ...
S100 calcium binding protein A5 (S100A5) belongs to the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 family members are localized in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such...
Structure of the Rat Vitamin D-Induced Calbindin-D9K Gene and Evolution of the EF-Hand Calcium-Binding Protein FamilyBased upon their number of calcium sites, two intracellular vitamin D-regulated calcium-binding proteins, CaBPs, (Calbindin-D9K and 28K) are expressed in specific target organs ...
Intracellular neuronal calcium sensor proteins: a family of EF-hand calcium-binding proteins in search of a function. Cell Tissue Res 1999; 295: 1–12. 104 Lautermilch NJ, Few AP, Scheuer T, Catterall WA. Modulation of CaV2.1 channels by the neuronal calcium-binding protein visinin-like ...
Structural Diversity in a Family of Homologous Proteins In this family, the EF-hand calcium-binding proteins, there are examples of at least three distinct mutual positions of the N and C-terminal domains, ... Krzysztof,Pawłowski,and,... - 《Journal of Molecular Biology》 被引量: 56发表...