EF-hand calcium-binding proteins can be classified as sensors or modulators of calcium signals. EF-hand calcium senor proteins need to transition from an 'off' state at the resting level of calcium in the cell, to an 'on' (activated) state when calcium signals increase the concentration of ...
EF-hand calcium-binding proteins. Curr Opin Struct Biol. 2000; 10(6):637- 643. [PubMed: 11114499]Lewit-Bentley A, Rety S (2000) EF-hand calcium-binding proteins. Curr Opin Struct Biol 10:637-643Lewit-Bentley, A,Rety, S.EF-hand calcium-binding proteins. Current Opinion . 2000...
该人EF-hand 钙结合域含蛋白 6,EFCAB6 GENLISA™ ELISA试剂盒产品的样本类型:血清、细胞培养物上清液和血浆检测范围是:Please refer to the current IFU for the updated calibrator range and sensitivity. 产品特点 该人EF-hand 钙结合域含蛋白 6,EFCAB6 GENLISA™ ELISA试剂盒产品的检测方法:比色法,450...
The majority of Ca2+-binding proteins belong to the EF-hand proteins, which contain a motif characterized by a helix–loop–helix structure, with an interhelical loop of 11 to 14 amino acids that can bind to Ca2+ ion13. In plants, the major family of EF-hand Ca2+-binding proteins ...
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Our results shed light on how the coupling between folding and ion binding contributes to the fine adjustment of the affinity for Ca in EF-hand proteins, which is crucial to function. 展开 关键词: Calcium Troponin C EF Hand Motifs Protein Binding Protein Folding Binding Sites Energy Transfer ...
The EF-hand protein with a helix-loop-helix Ca(2+) binding motif constitutes one of the largest protein families and is involved in numerous biological processes. To facilitate the understanding of the role of Ca(2+) in biological systems using genomic information, we report, herein, our impr...
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In EF-hand sites of known structure, the side chain provided by the ninth EF-loop position lies at the entrance of the shortest pathway connecting the cavity to solvent. The location of this residue suggests that it could serve as a "gateway", providing steric and electrostatic control over ...
Functional EF-hands seem always to occur in pairs. To date, the EF-hand homolog family contains more than 160 different -modulated which have a broad range of functions. Among them, are the , the , the , the , the S-100 and the 9- and 28 kDa. The most striking feature of the ...