Cite this chapter Perret, C., Lomri, Ne., Thomasset, M. (1990). Evolution of the “EF-Hand” Family of Calcium-Binding Proteins. In: Pochet, R., Lawson, D.E.M., Heizmann, C.W. (eds) Calcium Binding Proteins in Normal and Transformed Cells. Advances in Experimental Medicine and ...
The calcium signal is mediated and controlled by many proteins in the cell, the majority of which belong to the EF-hand super-family of calcium-binding proteins. EF-hand proteins are classified into calcium signal sensors and modulators. The calcium modulators fine-tune the shape and duration ...
EF-hand Ca 2+ binding proteins fall into two main categories: Ca 2+ buffers, which act as Ca 2+ chelators but do not undergo a conformational change; and Ca 2+ sensors, which, upon Ca 2+ binding, undergo a conformational change and transfer the signal to other proteins. Members of ...
Isolated calcium-binding loops of EF-hand proteins can dimerize to form a native-like structure Helix-loop-helix fragments of EF-hand proteins are known to dimerize in solution, re-producing the characteristic structure of native protein domains [Shaw... J Wójcik,J Góral,K Paw?Owski,... -...
The majority of Ca2+-binding proteins belong to the EF-hand proteins, which contain a motif characterized by a helix–loop–helix structure, with an interhelical loop of 11 to 14 amino acids that can bind to Ca2+ ion13. In plants, the major family of EF-hand Ca2+-binding proteins ...
S100A8 is a part of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a broad range of cells, and participate in the regulation of cellular processes such as cell cycle progression and differentiation. S100A8...
Calmodulin is a member of the EF-hand family of Ca2+-binding proteins. It consists of two homologous globular domains, each containing two helix-loop-helix... MA Starovasnik,D Su,K Beckingham,... - 《Protein Science》 被引量: 53发表: 2010年 Mining Calcium-binding Sites from Protein Str...
FhCaBP3: A Fasciola hepatica calcium binding protein with EF-hand and dynein light chain domainsFhCaBP3: A Fasciola hepatica calcium binding protein with EF-hand and dynein light chain domainsEF-handTrematodeCalciumbindingproteinLiverfluke\\{DLC\\}A...
EF hand calcium-binding domain A highly conserved calcium-binding domain, comprising two helices (E and F after the fifth and sixth helices of parvalbumin) that are linked by a short acidic calcium-binding loop that coordinates the calcium ion in a pentagonal bipyramidal arrangement. EF hands are...
A multigenic family of Ca2+-binding proteins of the EF-hand type known as S100 comprises 19 members that are differentially expressed in a large number of cell types. Members of this protein family have been implicated in the Ca2+-dependent (and, in some cases, Zn2+- or Cu2+-dependent)...