The calcium-binding EGF-like (cbEGF) domain is a common module found in functionally diverse extracellular proteins. Its importance is highlighted by a number of inherited diseases caused by missense mutations within the domain. It is characterised by six cysteine residues which normally disulphide ...
The calcium-binding EGF-like (cbEGF) domain is a common module found in functionally diverse extracellular proteins. Its importance is highlighted by a number of inherited diseases caused by missense mutations within the domain. It is characterised by six cysteine residues which normally disulphide bo...
Human Collagen and calcium-binding EGF domain-containing protein 1 (CCBE1) ELIS abx576671由上海拜力生物科技有限公司供应,该产品简介:Human Collagen and calcium-binding EGF domain-containing protein 1 (CCBE1) ELISA Kit
egf-likecalcium-bindingsite网络表皮生长因子样钙结合位点 网络释义 1. 表皮生长因子样钙结合位点 ...表皮生长因子功能域(EGFlikedomain)和表皮生长因子样钙结合位点(EGF-likecalcium-bindingsite),与Fibrillin蛋白家族的特点 …new.med.wanfangdata.com.cn|基于1 个网页©...
The known roles for calcium-binding proteins in developmental signaling pathways are reviewed. Current information on the calcium-binding characteristics of three classes of cell-surface developmental signaling proteins (EGF-domain proteins, cadherins and integrins) is presented together with an overview of...
Fibrillin-1 cbEGF domain calcium binding is mechanosensitive. (A,B) Snapshots from lowest energy SMD trajectory reveal gross conformational changes in cbEGF12-cbEGF13 calcium binding pockets over 50% strain (~ 60 Å to ~ 90 Å). Purple arrows indicate β-hairpin of calcium binding ...
EtMIC4 is a 240 kDa transmembrane protein from Eimeria tenella that contains 31 tandemly arranged epidermal growth factor (EGF), like repeats within its extracellular domain. The majority of these repeats have calcium binding (cb) consensus sequences. Little is known about cbEGFs in apicomplexan ...
Effect of deleting four Toxoplasma gondii calcium-binding EGF domain-containing proteins on parasite replication and virulence Xin-Cheng Wang Ting-Ting Li Xing-Quan Zhu Parasitology Research (2023) Screening the Toxoplasma kinome with high-throughput tagging identifies a regulator of invasion and egres...
The motif might function as a Ca2+-binding EGF (cbEGF) domain. Binding of Ca2+ to the cbEGF domain might cause a conformational change in the PV72 molecule to make the receptor-ligand complex stable. On the other hand, reduction of the environmental Ca2+concentration might cause the ...
Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by th...