C1-inhibitor deficiencyicatibantIcatibant, a bradykinin B2 receptor antagonist, is an established treatment for acute attacks of hereditary angioedema (HAE) with C1-inhibitor (C1-INH) deficiency. We describe our experience with icatibant in eight patients with angioedema because of acquired C1-INH ...
C1 inhibitorecallantideicatibanttranexamic acidINTRODUCTION: is a localized and self-limiting edema of the subcutaneous and submucosal tissue. with (C1-INH-) is the best characterized form of . In C1-INH-, the reduced plasma levels of C1-INH cause instability of the contact system with release...
Most patients who have hereditary angioedema receive treatment with androgens or impeded androgens. epsilon-Aminocaproic acid (EACA) is another treatment for C1 inhibitor deficiency. In two patients with angioedema and attacks of abdominal pain due to C1 inhibitor deficiency, long-term treatment with ...
There is no widely approved treatment for acute attacks of angioedema although several promising drugs are now in the final stages of clinical trials. 展开 关键词: complement C1 inhibitor (C1INH) hereditary angioedema acquired C1 inhibitor deficiency ...
Acquired C1 esterase inhibitor deficiency is a clinical syndrome closely resembling hereditary angioedema in which most patients have an associated malignancy of B cell lineage. Sera from 33 patients with B cell neoplasms were assayed for C1 esterase inhibitor level by rocket immunoelectrophoresis. The ...
C1-inhibitor deficiency and angioedema Correct prophylactic treatment is based on attenuated androgens in HAE and on antifibrinolytic agents in AAE. Life threatening laryngeal attacks and severe ... A Carugati,E Pappalardo,LC Zingale,... - 《Molecular Immunology》 被引量: 405发表: 2001年 Autoimmune...
C1 Esterase Inhibitor Transfusions in Patients with Hereditary Angioedema Background Hereditary angioedema results from the deficiency of C1-esterase inhibitor (C1-INH), and C1-INH replacement would represent definitive treatment... M,Michael,Glovsky - 《Annals of Allergy Asthma & Immunology》 被引量...
Acquired C1 esterase inhibitor deficiency in lymphomas: prevalence, symptoms, and response to treatment We retrospectively studied the prevalence of C1 esterase inhibitor (C1 INH) deficiency in 131 patients with various lymphomas. We determined C1 INH activit... C Bekos,T Perkmann,M Krauth,... -...
Acquired C1-inhibitor (C1 INH) deficiency is usually found in association with an underlying disease that is believed to be responsible for increased C1 INH catabolism, ultimately leading to the development of C1 INH deficiency. We report a remarkable patient with acquired C1 INH deficiency in whom...
Falsely normal C4 in a case of acquired C1 esterase inhibitor deficiency A 59-year-old lady presented with recurrent angioedema without urticaria. The clinical history and examination were consistent with an acquired C1 esterase... A Mclean-Tooke,C Stroud,A Sampson,... - 《Journal of Clinical ...