C1 esterase inhibitorcomplementgene therapyhereditary angioedemavascular permeabilityBackground Hereditary angioedema (HAE) is a life‐threatening, autosomal dominant disorder characterized by unpredictable, episodic swelling of the face, upper airway, oropharynx, extremities, genitalia, and gastrointestinal tract....
Recombinant human C1 esterase inhibitor for the treatment of hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE). The lack of C1 inhibitor function that results in excessive production of bradykinin causing the angioedema seen in hereditary angioedema (HAE) is well est... G Sabharwal...
Hereditary angioedema C1-esterase inhibitor replacement therapy and coexisting autoimmune disorders: findings from a claims databaseAngioedema, C1-inhibitor, autoimmune, complementBackground: Autoimmune diseases are a leading cause of morbidity and mortality in the US (estimated prevalence: 4.5%) and often...
(redirected from C1-esterase inhibitor deficiency)Also found in: Dictionary, Medical, Encyclopedia. Graphic Thesaurus 🔍 Display ON Animation ON Legend Synonym Antonym Related </>embed</> oedemahydropsedemadropsyQuincke's edemaperiodic edemagiant hivesatrophedemaangioedema noun Synonyms for angioe...
Treatment with C1-esterase inhibitor concentrate in type I or II hereditary angioedema: A systematic literature review Hereditary angioedema (HAE) due to C1 esterase inhibitor (HAE C1-INH) deficiency is a rare genetic disorder presenting with recurrent episodes of skin swel... K Bork,I Steffensen...
产品名称 C1 Esterase Inhibitor (C1-INH) 别名 C1 酯酶抑制剂 (C1-INH) 规格或纯度 1.0 mg/mL,0.22 µm filtered 产品介绍 Protein Purity >95 % by SDS PAGE Extinction Coeff. A280 nm = 0.45 at 1.0 mg/mL Molecular Weight 110,000 Da (single chain) General Description The protease inhibi...
Hereditary angioedema (HAE) is a rare autosomal dominant disease due to C1 esterase inhibitor deficiency (C1-INH). The disease is characterized by subcutaneous and submucosal edema in the absence of urticaria due to the accumulation of bradykinin. This descriptive study aimed to evaluate the clinical...
Treatment focuses on symptom control with therapies that regulate bradykinin activity (C1-INH concentrate, icatibant, ecallantide, tranexamic acid, androgens) and treatment of any underlying conditions. 展开 关键词: Acquired angioedema C1 esterase inhibitor deficiency Rituximab Lymphoproliferative disorders ...
Feasibility of home infusion and self-administration of nanofiltered C1 esterase inhibitor for routine prophylaxis in patients with hereditary angioedema a... Hereditary angioedema (HAE) is a rare, chronic disease of C1 inhibitor deficiency. Study researchers evaluated the prevalence of home and self-...
rhC1INH: a new drug for the treatment of attacks in hereditary angioedema caused by C1-inhibitor deficiency Recombinant human C1 esterase inhibitor (rhC1INH) (Ruconest(), Pharming) is a new drug developed for the relief of symptoms occurring in patients with angi... L Varga,H Farkas - 《...