corticosteroidsforme frusteThe pulmonary vasculitides are a group of rare but serious disorders that require early recognition, accurate diagnosis, and effective therapy. Churg-Strauss syndrome (CSS) is classified as small vessel vasculitis. Four different definitions for the diagnosis of CSS have been ...
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Cells were pre-treated with each inhibitor (10 mM) 1 h before the treatment of CCN1 recombinant protein (1 mg ml À 1). We found that only GO6850 (PKC inhibitor) blocked CCN1-induced IL-10 secretion (Figure 3f). Taken together, CpG ODN-induced CCN1 augmented IL-10 secretion via ...
To this end, we exposed HT-LKO cells to the NAT10 inhibitor remodelin, which has been shown to normalize nuclear shape in LMNA knockdown cells and Progeria patient cells17. Remodelin significantly (p < 0.001) increased nuclear circularity in HT-WT and in HT-LKO cells (Fig. 5c), ...
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JNK2AS treatment induced the expression of the cyclin-dependent kinase inhibitor p21(Cip1/Waf1) in parental MCF-7, RKO, and HCT116 cells but not in the p53-deficient derivatives. That p21(Cip1/Waf1) expression contributes to the survival of JNK2AS-treated cells was supported by additional...
NOVEL SUBSTANCE C-1 优质文献 相似文献Contractile effects of okadaic acid, a novel ionophore-like substance from black sponge, on isolated smooth muscles under the condition of Ca deficiency. Okadaic acid (Halichondrine-A, OA) isolated from Halichondria okadai is a monocarboxylic acid with a uniq...
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