C-Myc过表达在MM的发生和发展中起着关键的作用,目前认为MM中C-Myc过表达的机制有以5种:(1)染色体易位。涉及C-Myc异常表达的染色体易位情况在新诊断的MM患者中占20%～50%,这些易位涉及免疫球蛋白(immunoglobulin,Ig)基因位点和一些非Ig融合伴侣基因,如46序...
RUNNINGTITLE:THEC-MYCQUADRUPLEXSEQUENCEINDUCESCELLDEATH Addresscorrespondenceto:DonaldM.Miller,JamesGrahamBrownCancerCenter,University ofLouisville,529SouthJacksonSt.,Louisville,Kentucky40202,Tel:(502)562-4585;Fax. (502)562-4368;Email:donaldmi@ulh
cell Biol,1988,8(3):963～973. [10]Collins S.Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line[J].Nature,1982,298:679～681. [11]Gopal V,Hulette B,Li Yaqin,et al.C-myc and C-myb expression in acute myelogenous leukemia[J].Leuk Res,1992,16(...
Express target protein with C-terminal Myc tag in mammalian cell •Depositor Beyotime •Publication Song et al. ONCOTARGET. 2017Feb 7;8(6):9108-9122. •Sequence Information D2672 pCMV-C-Myc-seq.txt For Details Add to cart Brief Information Name Catalog No. Size Description pCMV-C-Myc...
Sequence Analysis, DNAPrecipitin TestsCpG IslandsE-Box ElementsThe transcription factor Myc is induced by mitogenic signals and regulates downstream cellular responses. If overexpressed, Myc promotes malignant transformation. Myc modulates expression of diverse genes in experimental systems, but few are ...
Amino Acid Sequence Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu 一般描述 c-Myc 肽是一种合成肽,其氨基酸序列相当于人 c-Myc c 末端 410-419 位氨基酸。 包装 4, 25 mg in glass bottle 应用 用于在免疫测定中置换与抗 c-Myc 抗体结合的 c-Myc 标记融合蛋白。通过 c-Myc 肽成功抑制抗体结合,证明结...
This allows for the study of NF-kB dimers which bind to specific endogenous DNA sequences. How should I prepare my nuclear extract? Any of the following are compatible. Active Motif’s Nuclear Extract Kit (Cat. No. 40010/40410)** Preparation of Nuclear Extract protocol in the Appendix of ...
Desislava MARKOVA Peter LOIDL'Lalio DJONDJUROV'Andreeva M , Markova D , Loidl P , Djondjurov L ( 1992 ): Intranuclear compartmentalization of transcribed and nontranscribed c-myc sequences in Namalva-S cells . Eur J Biochem 207 : 887 – 894 ....
genes through binding the consensus sequence E box within the promoter region, it can also positively or negatively regulate other target genes. c-Myc participates the regulation of cell proliferation, differentiation, growth, apoptosis, cell cycle progression, cellular immortalization and oncogenic transfo...
[SEQUENCE] 特别提示:仅供科研使用,不得用于临床检验及治疗使用 ,严禁用于临床医疗及其他非科研用途! 价格说明 价格:商品在爱采购的展示标价,具体的成交价格可能因商品参加活动等情况发生变化,也可能随着购买数量不同或所选规格不同而发生变化,如用户与商家线下达成协议,以线下协议的结算价格为准,如用户在爱采购上完成...