While it has been known for some time that the c-Myc protein binds to random DNA sequences, no sequence-specific binding activity has been detected. At its carboxyl terminus, c-Myc contains a basic-helix-loop-helix (bHLH) motif, which is important for dimerization and specific DNA binding,...
Full length Clone DNA of Mouse Ras-related GTP binding C with N terminal Myc tag. 质粒 启动子 Enhanced CMV promoter 载体 pCMV3-N-Myc 标签序列 Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG 测序引物 T7( 5' TAATACGACTCACTATAGGG 3' ) ...
This and a closely related DNA sequence element have been defined previously as part of the binding sites for human transcription factors USF and TFE3, which specifically bind to the adenovirus major late promoter or the μE3 motif within the immunoglobulin heavy-chain enhancer, respectively. It ...
1203Da: the ten amino acid myc tag sequence is EQKLISEEDL (in single letter code). What are the applications for myc tag? The addition of the myc tag to a particular protein can be useful when an antibody is not available to the protein of interest. Using recombinant DNA technology, the...
Myc is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the...
SEQUENCES V-Myc骨髓细胞瘤病毒癌基因同源物(MYC)重组蛋白The target protein is fused with two N-terminal Tags, His-tag and GST-tag, its sequence is listed below. MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YS...
This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. ...
DNA sequence analysis of the genetic recombination between Igh6 and Myc in an uncommon BALB/c plasmacytoma, TEPC 1194. Immunogenetics 1996; 44:151-6.Kovalchuk AL, Potter M, Janz S. 1996. DNA sequence analysis of the genetic recombination between Igh6 and Myc in an uncommon BALB/c ...
The information of sequences could be found in Supplementary Table S2. Glioma cell lines in logarithmic phase were infected with lentivirus vectors with polybrene at a multiplicity of infection of 10 for 12 h, and then maintained in the new fresh complete medium. After 72 h infection, ...
The MYC CDS sequence was cloned into the pLVX-IRES-Puro vector (named pLVX-MYC), and then verified by DNA sequencing. The primer sequences for MYC amplification were listed in Supplementary table 1. The plasmids pLVX-MYC or the negative control (pLVX-NC) were co-transfected with the plasmid...