Although it has been demonstrated that stimulation of c‑Maf inducing protein (CMIP) expression is involved in podocyte damage, the molecular events during this process remain unclear. In the current study, CMIP‑induced proximal signaling was investigated by focusing on its effect on cofilin‑...
b, Incomplete depletion of c-MAF protein in RORγt+ Treg cells in Maf∆Treg mice shown by a representative flow cytometry graph from 3 independent experiments (left), and a compilation of mean fluorescence intensities (MFI) in RORγt− Treg cells and residual RORγt+ Treg cells (right...
Lanatoside C sensitizes glioblastoma cells to tumor necrosis factor-related apoptosis-inducing ligand and induces an alternative cell death pathway Neuro-oncol, 13 (11) (2011), pp. 1213-1224 CrossrefView in ScopusGoogle Scholar Cited by (0)All...
(c)TGF-β, IL-27 and ICOS differentially regulate IL-10 and IL-22 expression. By inducing c-Maf, a crucial transcriptional activator of IL-10 expression, TGF-β, IL-27 or ICOS promote IL-10 production in a variety of T cell subsets. On the other hand, all three factors potently ...
The oncogene c-maf is frequently overexpressed in multiple myeloma cell lines and patient samples and contributes to increased cellular proliferation in part by inducing cyclin D2 expression. To identify regulators of c-maf, we developed a chemical screen in NIH3T3 cells stably overexpressing c-maf...
The AH region of L-Maf has a distinct role in inducing endogenous δ-crystallin gene. Document Type: Research article DOI: http://dx.doi.org/10.1046/j.1365-2443.2002.00548.x Affiliations: 1: Graduate School of Biological Sciences, Nara Institute of Science and Technology, Takayama 8916-5,...
Grb2 expression was analyzed as a control for equal protein loading. All data are expressed as the mean value of triplicate determinations ± SE. The mRNA expression of IFNγ was significantly enhanced (at 6-12 hours) and that of the Th1-inducing transcription factor, T-bet,11 was also ...