c-Jun NH2-terminal kinases (JNKs) are members of the mitogen-activated protein kinase (MAPK) family that regulate multiple aspects of liver cell biology in the healthy and diseased liver. JNKs exert key functions in the control of proliferation, cell death, survival, and inflammation. ...
Jiang,YingShenZhe-YuChenZhang,LiangZhou,ZhuoHuang,Xing-YuTaoSun,NuoYu,Lu-KaiZhai,NaLi,ChaoJNK-dependentmannerregulatesneuronalaxonelongation(JNK)-interactingprotein-3(JIP3)c-JunNH2-terminalkinaseNeurobiology:publishedonlineApril10,2013Biol.Chem.10.1074/jbc.M113.464453AccessmostupdatedversionJBCAffinitySitesFin...
Both corresponded to the c-Jun NH2-terminal kinase (JNK) 3. In the present study, genomic cloning re- vealed that the JNK3 gene consists of 14 exons interrupted by 13 introns; its transcription-initiation site is within exon 3 and the termination codon lies in exon 14. Fluorescence in ...
JNK c-Jun NH2-terminal kinase SAPK stress-activated protein kinase NFκB nuclear factor κB PDTC pyrrolidine dithiocarbamate PMA phorbol 12-myristate 13-acetate BHA butylated hydroxyanisole kb kilobase IL interleukin EMSA electrophoretic mobility shift assay TBS-T Tris-buffered saline-Tween GST glutathion...
Two ubiquitously expressed isoforms of c-Jun N-terminal protein kinase (JNK), JNK1 and JNK2, have shared functions and different functions. However, the mo... J Liu,Y Minemoto,A Lin - 《Molecular & Cellular Biology》 被引量: 506发表: 2004年 c-Jun NH2-Terminal Kinase (JNK)1 and JNK...
The c-Jun NH2-terminal kinase (JNK) is involved in the regulation of cell death, but its role in tumor necrosis factor (TNF)-alpha- and Fas-mediated apopto... Schwabe,F R. - 《Faseb Journal》 被引量: 666发表: 2004年 Paclitaxel-resistant Human Ovarian Cancer Cells Undergo c-Jun NH2-...
c-Jun_N-terminal_kinase抑制剂_激动剂_MCE JNK c-Jun N-terminal kinase protein kinase family, and are responsive to stress stimuli, such as cytokines,ultraviolet irradiation, heat shock, and osmotic shock. JNKs play a role in T cell differentiation and the cellular apoptosis pathway.Activation ...
Biologic sequelae of c-Jun NH(2)-terminal kinase (JNK) activation in multiple myeloma cell lines. Oncogene 2003;22:8797-801.Hideshima T., Hayashi T., Chauhan D., Akiyama M., Richardson P. and Anderson K. Biologic sequelae of c-Jun NH2-terminal kinase (JNK) activation in multiple ...
c-Jun NH2-Terminal Kinase 2α2 Promotes the Tumorigenicity of Human Glioblastoma Cells c-Jun NH-terminal kinases (JNK) are members of the mitogen-activatedprotein kinase family and have been implicated in the formationof several human tumors,... J Cui,SY Han,C Wang,... - 《Cancer Research...
8.1.7CDK5 as an upstream regulator of c-Jun NH2-erminal kinase cascade Deregulated Cdk5 induces a biphasic activation of c-Jun (Fig. 7). The c-Jun NH2-terminal kinase (JNK, aka SAPK) a member of the subfamily of mitogen-activated protein kinases (MAPKs) is activated by a variety of ...