c-Jun NH2-terminal kinases (JNKs) are members of the mitogen-activated protein kinase (MAPK) family that regulate multiple aspects of liver cell biology in the healthy and diseased liver. JNKs exert key functions in the control of proliferation, cell death, survival, and inflammation. ...
(JIP3)c-JunNH2-terminalkinaseNeurobiology:publishedonlineApril10,2013Biol.Chem.10.1074/jbc.M113.464453AccessmostupdatedversionJBCAffinitySitesFindarticles,minireviews,ReflectionssimilartopicschoosefromallJBC'se-mailalertsClickherearticleciteswhichcanaccessedfreec-JunNH-terminalkinase(JNK)-interactingprotein-3(JIP3...
c-Jun NH-terminal kinases (JNK) are members of the mitogen-activatedprotein kinase family and have been implicated in the formationof several human tumors, especially gliomas. We have previouslyshown that a 55 kDa JNK isoform is constitutively active in86% of human brain tumors and then showed...
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Both corresponded to the c-Jun NH2-terminal kinase (JNK) 3. In the present study, genomic cloning re- vealed that the JNK3 gene consists of 14 exons interrupted by 13 introns; its transcription-initiation site is within exon 3 and the termination codon lies in exon 14. Fluorescence in ...
RA, Le Gros G, Davis RJ, Rincon M (2002) c-Jun NH(2)-terminal kinase (JNK)1 and JNK2 have distinct roles in CD8(+) T cell activation. J... Dietrich,Conze,Troy,... - 《Journal of Experimental Medicine》 被引量: 189发表: 2002年 Activation of c-Jun NH2-terminal kinase (JNK) ...
the functional role of c-Jun NH2 -terminal kinase (JNK) during infection-induced thymic atrophy was addressed. The levels of phosphorylated JNK in immature CD4(+) CD8(+) thymocytes from C57BL/6 (Nramp-deficient) and 129/SvJ (Nramp-sufficient) mice were increased upon oral infection of...
In this study we show that the structurally unrelated antioxidant agents pyrrolidine dithiocarbamate (PDTC), butylated hydroxyanisole, and Nacetylcysteine activated JNK (c-Jun NH2-terminal kinase) in Jurkat T cells. This activation differed substantially from that mediated by phorbol 12-myristate 13-...
Biologic sequelae of c-Jun NH(2)-terminal kinase (JNK) activation in multiple myeloma cell lines. Oncogene 2003;22:8797-801.Hideshima T., Hayashi T., Chauhan D., Akiyama M., Richardson P. and Anderson K. Biologic sequelae of c-Jun NH2-terminal kinase (JNK) activation in multiple ...
c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells. 来自 NCBI 喜欢 0 阅读量: 101 作者: Zou,W....