Jun NH2-Terminal KinaseJun NH2-terminal kinase (JNK) is mitogenic activated protein (MAP) kinase involved with c-Jun phosphorylation and activation of NF-κB. Interleukin-1β (IL-1β)doi:10.1007/3-540-27806-0_852Vohr, Hans-WernerSpringer Berlin Heidelberg...
Both corresponded to the c-Jun NH2-terminal kinase (JNK) 3. In the present study, genomic cloning re- vealed that the JNK3 gene consists of 14 exons interrupted by 13 introns; its transcription-initiation site is within exon 3 and the termination codon lies in exon 14. Fluorescence in ...
c-Jun NH-terminal kinases (JNK) are members of the mitogen-activatedprotein kinase family and have been implicated in the formationof several human tumors, especially gliomas. We have previouslyshown that a 55 kDa JNK isoform is constitutively active in86% of human brain tumors and then showed...
医学/心理学--基础医学 系统标签: axonjnkneuronalinteractingregulateskinase Jiang,YingShenZhe-YuChenZhang,LiangZhou,ZhuoHuang,Xing-YuTaoSun,NuoYu,Lu-KaiZhai,NaLi,ChaoJNK-dependentmannerregulatesneuronalaxonelongation(JNK)-interactingprotein-3(JIP3)c-JunNH2-terminalkinaseNeurobiology:publishedonlineApril10,2013...
Biologic sequelae of c-Jun NH(2)-terminal kinase (JNK) activation in multiple myeloma cell lines. Oncogene 2003;22:8797-801.Hideshima T., Hayashi T., Chauhan D., Akiyama M., Richardson P. and Anderson K. Biologic sequelae of c-Jun NH2-terminal kinase (JNK) activation in multiple ...
The c-Jun NH(2)-terminal kinase (JNK) signaling pathway is induced by cytokines and stress stimuli and is implicated in cell death and differentiation, but the specific function of this pathway depends on the cell type. Here we examined the role of JNK1 and JNK2 in CD8(+) T cells. Un...
c-Jun NH2-Terminal Kinase 2α2 Promotes the Tumorigenicity of Human Glioblastoma Cells c-Jun NH-terminal kinases (JNK) are members of the mitogen-activatedprotein kinase family and have been implicated in the formationof several human tumors,... J Cui,SY Han,C Wang,... - 《Cancer Research...
Phosphorylated c-Jun NH2-terminal kinase is overexpressed in human papillary thyroid carcinomas and associates with lymph node metastasis. Cancer Lett 2010;293:175-80.Phosphorylated c-Jun NH2-terminal kinase is overexpressed in human papillary thyroid carcinomas and associates with lymph node metastasis...
the functional role of c-Jun NH2 -terminal kinase (JNK) during infection-induced thymic atrophy was addressed. The levels of phosphorylated JNK in immature CD4(+) CD8(+) thymocytes from C57BL/6 (Nramp-deficient) and 129/SvJ (Nramp-sufficient) mice were increased upon oral infection of...
In this study we show that the structurally unrelated antioxidant agents pyrrolidine dithiocarbamate (PDTC), butylated hydroxyanisole, and Nacetylcysteine activated JNK (c-Jun NH2-terminal kinase) in Jurkat T cells. This activation differed substantially from that mediated by phorbol 12-myristate 13-...