OPEN Citation: Cell Death and Disease (2017) 8, e3058; doi:10.1038/cddis.2017.450 Official journal of the Cell Death Differentiation Association www.nature.com/cddis Inhibition of the deubiquitinase USP5 leads t
来自美国希德斯-西奈医疗中心的Shelly C Lu教授团队,利用小鼠慢性胆汁淤积致胆管癌模型和分析蛋白表达的情况,发现c-Myc,MATa1,MafG或c-Maf可以相互作用。接着,研究人员发现,将MATa1敲除或高表达MafG或c-Maf均可容易促进胆管癌的增长及侵袭能力。因此,c-Myc相...
c-Maf Protein information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices, suppliers, SDS and more, available at Chemicalbook.
Marked induction of c-Maf protein during Th17 cell differentiation and its implication in memory Th cell development. J. Biol. Chem. 286:14963-14971. http:// dx.doi.org/10.1074/jbc.M111.218867Marked induction of c-Maf protein during Th17 cell differentiation and its implication in memory Th ...
19. We therefore deletedMafwithFoxp3creto test its function in Tregcells. InH. hepaticus-colonizedMaffl/fl;Foxp3cre(Maf∆Treg) mice, despite incomplete depletion of c-MAF protein (Extended Data Fig. 6b), there was a marked decrease in the proportion of RORγt+but not RORγt−Treg...
MAF (MAF BZIP Transcription Factor) is a protein coding gene located on human chromosome 16q23.2. MAF is also known as CCA4, AYGRP, c-MAF and CTRCT21. The human MAF gene encodes a 38492 Da protein containing 373 amino acids. The MAF protein is ubiquitously expressed in kidney, endometri...
suggesting its substrate specificity. In the functional studies, USP5 was found to promoted the transcriptional activity of c-Maf. Consistent with the high level of c-Maf protein in MM cells, USP5 was also highly expressed. When USP5 was knocked down, c-Maf underwent degradation. Interestingly...
RAS P21 Protein Activator 3 (RASA3) Specifically Promotes Pathogenic T Helper 17 Cell Generation by Repressing T-Helper-2-Cell-Biased Programs. Authors - Bing Wu View Article human WB Acta Pharmacol Sin Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis. Authors -...
激活蛋白-1家族JunB、c-Jun、c-Maf、c-Fos在多发性骨髓瘤中的表达
c-maf antibody Recombinant Human c-Maf protein c-Maf antibody, C-term Anti-EPCAM Recombinant Antibody Anti-Human Phosphatidylserine Recombinant Antibody His-tag Recombinant Monoclonal Antibody Polyubiquitinylated conjugates recombinant monoclonal antibody (UBQM) VEGF Recombinant monoclonal antibody (Rabbit IgG...