基本信息 文章标题:Integrative analysis of single‑cell and bulk RNA‑sequencing data revealed T cell marker genes based molecular sub‑types and a prognostic signature in lung adenocarcinoma发表时间:2024-01-10 发表杂志:Scientific Reports 影响因子:4.997 在线阅读链接: https://www.nature.com/articl...
整合单细胞数据和Bulk数据的多种方法(一):R包scAB 最近刷到NAR最新的一篇算法文章《scAB detects multiresolution cell states with clinical significance by integrating single-cell genomics and bulk sequencing data》,DOI10.1093/nar/gkac1109。通过整合单细胞基因组学(包括scRNA-seq和sc-ATAC-seq数据)和Bulk RNA...
Figure 3 IRG scores of PBMC cell clusters in AD. 3、对AD患者大脑的BulK-seq数据进行差异基因分析---DEGs of AD Brain From Bulk Sequencing Data BulK-seq数据数据集GSE33000,包括310例AD患者和157例对照组。 基于BulK-seq数据集以探索AD脑组织中的DEGs。在AD大脑中5,339 up and 5542 down-regulated DEG...
In this study, we have provided an accurate and robust method to identify clones of tumor heterogeneity and their evolutionary history by combining single-cell and bulk sequencing data.doi:10.1186/s12859-021-04338-7Baghaarabani, LeilaGoliaei, Sama...
Either data type alone has shortcomings with regard to this task, but methods integrating both data types have been lacking. Here, we present B-SCITE, the first computational approach that infers tumour phylogenies from combined single-cell and bulk sequencing data. Using a comprehensive set of ...
3、对AD患者大脑的BulK-seq数据进行差异基因分析---DEGs of AD Brain From Bulk Sequencing Data BulK-seq数据数据集GSE33000,包括310例AD患者和157例对照组。 基于BulK-seq数据集以探索AD脑组织中的DEGs。在AD大脑中5,339 up and 5542 down-regulated DEGs were retained in AD brains (Figure 4A)。热图展示...
Identification of the Immune Subtype of Hepatocellular Carcinoma for the Prediction of Disease-Free Survival Time and Prevention of Recurrence by Integrated Analysis of Bulk- and Single-Cell RNA Sequencing Data 基于bulk转录组数据和单细胞转录组数据鉴定肝癌免疫亚型并预测无病生存期和复发 摘要 背景:影响肝...
近日,美国俄勒冈健康与科学大学计算生物学组夏铮团队在Nature Biotechnology上发表了题为“Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data”的研究文章。研究团队开发了Scissor算法,可利用大量单...
Power and pitfalls of computational methods for inferring clone phylogenies and mutation orders from bulk sequencing dataCancer genomicsTumour heterogeneitySimulated clone phylogenies and tumor composition. ( , ) Phylogeny and frequencies of seven clones in seven tumor samples (T1-T7) derived from EV005...
to use these tools, see theDemuxlet section down below. For more information on Demuxlet and Mux-sequencing, see theDemuxlet GitHub Page. (Impetus: Many Mux-seq experiments will involve generating the side-by-side bulk and single-cell RNAseq data like the rest of the package is built for...