早!今天小编和大家分享一篇22年11月发表在Frontiers in Immunology(IF:8.786)杂志的文章《Identification and validation of a signature based on macrophage cell marker genes to predict recurrent miscarriage by integrated analysis of si...
Scissor发表在2021年Nature Biotechnology上,题为《Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data》。和scAB算法一样,Scissor算法可利用单细胞数据和bulk RNA-seq数据及表型信息识别与疾病高度相关的细胞亚群。 image-20230125165155292 本文将介绍: Scissor算法的工作流程;...
single-cell RNA sequencingLow back pain (LBP) is a prevalent health problem worldwide that affects over 80% of adults during their lifetime. Intervertebral disc degeneration (IDD) is a well-recognized leading cause of LBP. IDD is classified into five grades according to the Pfirrmann ...
早!今天小编和大家分享一篇22年11月发表在Frontiers in Immunology(IF:8.786)杂志的文章《Identification and validation of a signature based on macrophage cell marker genes to predict recurrent miscarriage by integrated analysis of single-cell and bulk RNA-sequencing》。作者通过单细胞和bulk RNA测序的联合分析...
今天小编和大家分享一篇22年11月发表在Frontiers in Immunology(IF:8.786)杂志的文章《Identification and validation of a signature based on macrophage cell marker genes to predict recurrent miscarriage by integrated analysis of single-cell and bulk RNA-sequencing》。作者通过单细胞和bulk RNA测序的联合分析,...
Single-cell RNA sequencing EMT: Epithelial-mesenchymal transition RNA-Seq: RNA-sequencing TCGA: The Cancer Genome Atlas GTEx: Genotype-Tissue Expression 2D: Two-dimensional 3D: Three-dimensional TDO: Tumor-derived organoids H&E: Hematoxylin and eosin ...
Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer Ignasius Joanito, Pratyaksha Wirapati, Nancy Zhao, Zahid Nawaz, Grace Yeo, Fiona Lee, Christine L. P. Eng, Dominique Camat Macal...
以单细胞分辨率揭示组织分子结构有助于更好地了解生物体的生物学和病理过程。然而,bulk RNA-seq 只能测量细胞混合物中的基因表达。《Nature Communications》发表了一种基于深度学习框架的空间去卷积算法:Bulk2Space,首次实现将Bulk转录组重构至单细胞空间分辨率。
Single-cell sequencing is frequently affected by “omission” due to limitations in sequencing throughput, yet bulk RNA-seq may contain these ostensibly “omitted” cells. Here, we introduce the single cell trajectory blending from Bulk RNA-seq (BulkTrajBlend) algorithm, a component of the OmicVer...
Atf4 regulates angiogenic differences between alveolar bone and long bone macrophages by regulating M1 polarization, based on single-cell RNA sequencing, RNA-seq and ATAC-seq analysis. J Transl Med. 2023 Mar 14;21(1):193. doi: 10.1186/s12967-023-04046-1. PMID: 36918894; PMCID: PMC10012539...