细胞成分主要集中在细胞外区域、转录因子复合物和染色质中(图 2C)。在分子功能类别中,差异 T 细胞标记基因主要与相同的蛋白质结合、信号受体结合和 DNA 结合转录激活因子活性、RNA 聚合酶 II 特异性相关(图 2D)。KEGG分析结果表明这些基因与癌症、人类T细胞白血病病毒1感染、细胞凋亡途径和IL-17信号通路显著相关(...
文章标题:Integrated Bulk and Single-cell RNA Sequencing Data Constructs and Validates a Prognostic Model for Non-small Cell Lung Cancer发表时间:2024-01-01 发表杂志:Journal of Cancer 影响因子:3.9 在线阅读链接:https://www.jcancer.org/v15p0796.htm ...
今天小编和大家分享一篇22年11月发表在Frontiers in Immunology(IF:8.786)杂志的文章《Identification and validation of a signature based on macrophage cell marker genes to predict recurrent miscarriage by integrated analysis of single...
今天给大家介绍的就是这篇发表在《Frontiers in Genetics》上题为"Integrated analysis of bulk and single-cell RNA sequencing reveals the interaction of PKP1 and tumor-infiltrating B cells and their therapeutic potential for nasopharyngeal carcinoma"的文章,IF=4.8。作者在文章的Acknowledgement也是对我们进行了...
今天小编和大家分享一篇22年11月发表在Frontiers in Immunology(IF:8.786)杂志的文章《Identification and validation of a signature based on macrophage cell marker genes to predict recurrent miscarriage by integrated analysis of single-cell and bulk RNA-sequencing》。作者通过单细胞和bulk RNA测序的联合分析,...
Bulk RNA数据基于细胞群体水平获得组织的平均特性,反映细胞群体的平均差异,而Single-cell RNA通过单个细胞的mRNA进行转录组分析,识别不同细胞亚群的细胞类型、状态和谱系,绘制细胞图谱、鉴定细胞异质性,可以精准解析细胞亚类功能及对疾病的影响[...
今天小编和大家分享一篇22年11月发表在Frontiers in Immunology(IF:8.786)杂志的文章《Identification and validation of a signature based on macrophage cell marker genes to predict recurrent miscarriage by integrated analysis of single-cell and bulk RNA-sequencing》。作者通过单细胞和bulk RNA测序的联合分析,...
文章标题:Integrated Bulk and Single-cell RNA Sequencing Data Constructs and Validates a Prognostic Model for Non-small Cell Lung Cancer 发表时间:2024-01-01 发表杂志:Journal of Cancer 影响因子:3.9 在线阅读链接:https://www.jcancer.org/v15p0796.htm ...
本期分享一篇整合单细胞和bulk-RNA seq数据分析的文章,揭示了抗原呈递和过程中的肿瘤相关成纤维细胞,并建立了前列腺癌的预测特征模型。文章于2024年1月发表于《Journal of Translational Medicine》,通讯作者为上海交通大学的韩邦旻教授,标题“Integrating single-cell and bulk RNA sequencing data unveils antigen presenta...
今天给大家介绍的就是这篇发表在《Frontiers in Genetics》上题为"Integrated analysis of bulk and single-cell RNA sequencing reveals the interaction of PKP1 and tumor-infiltrating B cells and their therapeutic potential for nasopharyngeal carcinoma"的文章,IF=4.8。作者在文章的Acknowledgement也是对我们进行了...