The two Kaplan-Meier curves represent the overall survival probabilities of triple negative breast cancer patients with either positive or negative androgen receptor tumors. The green curve (labelled "Positive"; "Group: Pos") represents 18 androgen receptor positive patients ("number at risk") which...
(22%) n=402 (46%) 317 (79%) 85 (21%) n=355 (48%) 272 (77%) 83 (23%) PR=Progesterone receptor; ER=Estrogen receptor; pos=positive; neg=negative (cut- off 15 fmol mg71); pre-op=pre-operative; decrease=maximal decrease of the pre- op value within 6 months post-operatively....
Triple negative breast cancer (TNBC) accounts for 15–20% of breast cancer cases in the United States. Systemic neoadjuvant chemotherapy (NACT), with or without immunotherapy, is the current standard of care for patients with early-stage TNBC. However, up to 70% of TNBC patients have significa...
breast cancer and TAM on UFT + MM in patients with estrogen-receptor-negative [ER(-)] breast cancer.Methods: MM (13 mg/m2) was intravenously administered on the day of surgery for all patients, after which patients with ER(+) were randomised to TAM 20 mg/day (treatment A) or TAM 20...
American Joint Committee on Cancer CNA: Copy number alteration HR+: Hormone receptor-positive HRD: Homologous recombination deficiency IBC: Inflammatory breast cancer IHC: Immunohistochemistry Mb: Megabase NGS: Next-generation sequencing non-IBC: Non-inflammatory breast cancer SNV: Single nuc...
Treated invasive cancer (residual) K: Nearest neighbor number LEDs: Light-emitting diodes LUT: Look-up table MVA: Mean vessel area MVD: Mean vessel density Neg: Negative NIR: Near-infrared NOR: Normal NPV: Negative predictive value OCT: Optical coherence tomography Pos: Positive...
MAPK mitogen-activated protein kinase MMP matrix metallopeptidase Neg negative NPC1 Niemann-pick c1 protein NRH2 nucleolar RNA helicase 2 OS overall survival Pos positive PR progesterone receptor. ‡‡ Present address: Alphalyse A/S, Unsbjergvej 4, DK-5220 Odense SØ, Denmark. ...
Here we analysed the expression of L1CAM breast cancer subtypes. Methods: We analyzed mRNA and protein expression data from different breast cancer cohorts for L1CAM, estrogen receptor, progesterone receptor, Her-2 and Androgen receptor (AR) and correlated the data. We performed Western blot ...
b, Gene ontology enrichment analysis showing top enriched biological process gene sets associated with each cell state (Pos: positive; Neg: negative; Reg: regulation; RSTK: receptor protein serine/threonine kinase; TGF: transforming growth factor; IGF: insulin-like growth factor). c, CODEX data ...
Categories labels are as follows: RNA groups (RNA.A, RNA.B, RNA.C and RNA.D); PAM50 subtypes (LumB, Her2, Basal); ER status (ER.POS, ER.NEG), PR status (PR.POS, PR.NEG); TP53 mutations: (TP53.M, TP53.WT); fraction of genome altered (FGA.L (lower quartile), FGA.H (...