Estrogen receptor beta in breast cancer. Endocrine-Related Cancer 9, 1-13.Haldosen LA, Zhao C, Dahlman-Wright K. Estrogen receptor beta in breast cancer. Mol Cell Endocrinol. 2014; 382:665-672.Palmieri C, Cheng GJ, Saji S, et al. Estrogen receptor beta in breast cancer. Endocrine-...
The estrogen receptor (ER) assay is widely used to select sensitivity to hormone therapy in patients with breast cancer. Recently, a new form of ER, known as ERβ was identified, the classic form now being denoted ERα. In this investigation, ERα and ERβ were measured at the mRNA ...
Estrogen receptor-positive breast cancer: a multidisciplinary challenge. Wiley Interdisciplinary Reviews. Systems Biology and Medicine . 2011; 3 (2):216–230.Zwart W, Theodorou V, Carroll JS. Estrogen receptor-positive breast cancer: a multidisciplinary challenge. Wiley Interdiscip Rev Syst Biol Med ...
Two potential explanations for this over-representation of lobular breast cancer could be envisaged. It may be presumed that higher estrogen receptor α expression in lobular breast cancer might play a role, but a considerably higher share of lobular breast cancer was present in both, the estrogen...
While CDK4/6 inhibitors (CDK4/6i) have improved outcomes for breast cancer patients, estrogen receptor (ER + ) breast cancers often develop resistance, and triple negative breast cancer (TNBC) show poor sensitivity. Here, the authors identify a vulnerability of CDK4/6i treated ER+ and ...
Estrogen receptor-positive, progesterone receptor-negative, and human epidermal growth factor receptor 2 (HER2)-negative (ER+PR-HER2-) breast cancer comprise a special type of breast cancer that constitutes ~10% of all breast cancer patients. ER+PR-HER2- tumor benefits less from endocrine therapy...
Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, CH-1015, Lausanne, Switzerland. cathrin.brisken@epfl.ch, Breast Cancer Now Research Centre, Institute of Cancer Research, London, UK. cathrin.brisken@epfl.ch....
Frozen sections of breast tumor tissue have been stained using an immunoperoxidase [estrogen receptor (ER)-immunocytochemistry] kit incorporating a monoclo... RA Mcclelland,P Finlay,KJ Walker,... - 《Cancer Research》 被引量: 230发表: 1990年 Truncated forms of DNA-binding estrogen receptors in...
The majority of breast cancers express the estrogen receptor (ERα) and agents targeting this pathway represent the main treatment modality. Endocrine therapy has proven successful in the treatment of hormone-responsive breast cancer since its early adoption in the 1940s as an ablative therapy. Unfor...
incidence of breast cancer continues to rise in many parts of the world. Among breast cancers, triple-negative breast cancer (TNBC) sub-type is one of the aggressive breast cancers as TNBC cells lack all three currently targetable molecules such as estrogen receptor, progesterone receptor, and ...