[3]Oh M, Alkhushaym N, Fallatah S, et al. The association of BRCA1 and BRCA2 mutations with prostate cancer risk, frequency, and mortality: A meta-analysis. Prostate. 2019;79(8):880-895. doi:10.1002/pros.23795 [4]Hu C, Hart SN, Polley EC, et al. Association Between Inherited Ge...
[3]Oh M, Alkhushaym N, Fallatah S, et al. The association of BRCA1 and BRCA2 mutations with prostate cancer risk, frequency, and mortality: A meta-analysis. Prostate. 2019;79(8):880-895. doi:10.1002/pros.23795 [4]Hu C, Hart SN, Polley EC, et al. Association Between Inherited Ge...
[3]Oh M, Alkhushaym N, Fallatah S, et al. The association of BRCA1 and BRCA2 mutations with prostate cancer risk, frequency, and mortality: A meta-analysis. Prostate. 2019;79(8):880-895. doi:10.1002/pros.23795 [4]Hu C, Hart SN, Polley EC, et al. Association Between Inherited Ge...
BRCA2突变男性,同时患上乳腺癌和前列腺癌 男性乳腺癌是一种罕见的恶性肿瘤,文献报道其在新发乳腺癌中占比<1%,其预后相比于女性乳腺癌要差。美国MD安德森癌症中心曾在新英格兰医学杂志(NEJM)发表了男性乳腺癌的综述论文1,文章中列出了男性乳腺...
BRCA1 and BRCA2 pathogenic variants (PVs) are associated with prostate cancer (PCa) risk, but a wide range of relative risks (RRs) has been reported. We systematically searched PubMed, Embase, MEDLINE and Cochrane Library in June 2021 for studies that es
[3]Oh M, Alkhushaym N, Fallatah S, et al. The association of BRCA1 and BRCA2 mutations with prostate cancer risk, frequency, and mortality: A meta-analysis. Prostate. 2019;79(8):880-895. doi:10.1002/pros.23795 [4]Hu C, Hart SN, Polley EC, et al. Association Between Inherited Ge...
We found that carriers of BRCA2 mutations have a high risk of developing prostate cancer, particularly more aggressive prostate cancer, and that this risk varies by family history of prostate cancer and the location of the mutation within the gene....
Germline mutations in the breast cancer predisposition gene 2 (BRCA2) are the genetic events known to date that confer the highest risk of prostate cancer (8.6-fold in men 鈮 65 years). Although the role of BRCA2 and BRCA1 in prostate tumorigenesis remains unrevealed, deleterious mutations ...
risk of breast and ovarian cancers in female carriers, and knowledge ofBRCA1/2PVs informs established cancer screening and options for risk reduction. While risks to male carriers ofBRCA1/2PVs are less characterized, there is convincing evidence of increased risk for prostate cancer, pancreatic ...
19、te cancer with brca1 and brca2 founder mutationsj.clinical cancer research,2009,15(3):1112-1120.7 oh m,alkhushaym n,fallatah s,et al.the association of brca1 and brca2 mutations with prostate cancer risk,frequency,and mortality:a meta-nalysisj.the prostate,2019,79(8):880-895.8 try...