The second part is an overview of the therapeutic compounds used for breast cancer treatment targeting BRCA1, and thenatural food components that hold potential preventive effect against those types of breast cancer in which BRCA1 expression is either reduced or lacking. Further studies elucidating ...
and its incidence continues to rise. Postoperative radiotherapy for breast cancer can effectively improve local control rate and long-term survival rate. Radiotherapy has become the main technique for breast cancer treatment. How t...
- 《Breast Cancer Res Treat》 被引量: 6发表: 2017年 Ruthenium complexes for breast cancer therapy There has been a great deal of interest in using ruthenium-based complexes to treat breast cancer. Several species have shown potential as treatment ... S Sadique,AA Baqer,AW Salman,... - ...
To determine whether down-regulation of BRCA1 could affect breast cancer stem cell fate, we knocked-down BRCA1 in the BRCA1-competent human breast cancer cell line SKBR3 using RNA interference (Fig. 3A). Interestingly, siBRCA1 treatment resulted in significant increase in the expression of ...
【For those with triple negative recurrent/stage IV breast cancer and germline BRCA1/2 mutations, the NCCN Panel has included platinum agents (cisplatin and carboplatin) as preferred treatment options.】在这种情况下,PARP...
术语“治疗(treating/treatment)”是指在治疗或改善损伤、疾病、病变或病状方面的任何成功迹象,包括任何客观或主观参数,诸如减轻;缓解;减弱症状或使得损伤、病变或病状更可为患者耐受;减缓退化或衰退速率;使得退化终点的致虚弱性较小;改进患者的身体或精神健康状态。对症状的治疗或改善可基于客观或主观参数;包括身体检查...
first PARPi to be approved in breast cancer. DeterminingBRCA1/2 mutation status in this breast cancer subgroup could potentially expand treatment options beyond the current standard of taxane and anthracycline-based chemotherapy. Although attempts have been made to develop scoring systems that measure ...
In establishing decision models in the treatment and prevention of breast cancer, it is important to evaluate patients' preferences for such interventions. The objectives of the present study were: (i) to characterize women's preferences for breast cancer treatments and BRCA1/BRCA2 testing, using ...
The role of single drugs in the treatment of neuroblastoma is poorly defined. We, therefore, tested neuroblastoma cell survival after a 72 h exposure to on... S Fulda,M Honer,I Menke-Moellers,... - 《European Journal of Cancer》 被引量: 55发表: 1995年 加载更多来源...
10.Peter A. Fasching, Sibylle Loibl, Chunling Hu, et al. BRCA1/2 Mutations and Bevacizumab in the neoadjuvant treatment of breast cancer: response and prognosis results in patients with triple- negative breast cancer f...