[9] Brekelmans CT, Tilanus-Linthorst MM, Seynaeve C, et al. Tumour characteristics, survival and prognostic factors of hereditary breast cancer from BRCA2-, BRCA1- and non-BRCA1/2 families as compared to sporadic br...
Assessing the risk of uterine serous carcinoma in survivors of triple negative breast cancer: Is BRCA1 the link? 评估三阴性乳腺癌幸存者患子宫浆液性癌的风险:BRCA1是联系吗? First Author: William Manning Background Uterine ...
Recent advances in revealing the molecular mechanisms of antler regeneration [6, 7] have highlighted the potential of this mammalian model of natural regeneration whereby even with extreme rates of cell proliferation, the resultant-tissue remains remarkably cancer-free [8, 9]. Deer antlers are the ...
breast cancerM酶ller P, M忙hle L, Vab酶 A, Clark N, Sun P, Narod SA. Age-specific incidence rates for breast cancer in carriers of BRCA1 mutations from Norway. Incidence rates of breast cancer among women with a BRCA1 mutation vary according to their reproductive histories and country ...
Breast cancer rates and median age of onset differ between Western Europe and North Africa. In Western populations, 5 to 10 % of breast cancer cases can be attributed to major genetic factors such asBRCA1andBRCA2, while this attribution is not yet well defined among Africans. To help determi...
The rates for BRCA1/2 genetic testing varied by the clinical indications (p < 0.001). Patients with a family history of breast cancer or personal history of ovarian cancer had higher rates of germline BRCA1/2 testing (41.4% and 57.9%, respectively, Additional file 1: Table S1). The...
70)ofbreastcancersandtheadjacentatypicalhyperplasia.LossofexpressionofBRCA1,BRCA2,PTEN,RbproteinsWasfoundin 2.9%(2/69),6.3%(4/63),5.1%(3/59),5.4%(3/56)ofbreastcancersandtheadjacentatypicalhyperplastictissues,respective· ly.(2)Aberantexpressionoftwotumorsuppressorgeneswasfoundin4.6%ofsamples.Aberant...
Results: The positive rates of BRCA1 gene were 50.5%(48/95)in breast cancer tissues and 89.3%(25/28)in adenosis tissues, while in breast cancer adjacent tissues, the rates were 66.3%(63/95).The positive rates of BRCA2 gene were 52.6%(50/95)in breast cancer tissues and 92.9%(26/28...
BRCA1/2 mutation testing in breast cancer patients: a prospective study of the long-term psychological impact of approach during adjuvant radiotherapy Breast Cancer Res Treat, 109 (2008), pp. 507-514 CrossrefView in ScopusGoogle Scholar 15 I.H. Ismail, R. Davidson, J.P. Gagné, Z.Z. Xu...
7.Byrski T, Huzarski T, Dent R, et al: Pathologic complete response to neoadjuvant cisplatin in BRCA1-positive breast cancer patients. Breast Can- cer Res Treat 147:401-405, 2014 8.Byrski T, Gronwald J, Huzarski...