Mesenchymal Stem Cell-Secreted Exosomes and Soluble Signals Regulate Breast Cancer Metastatic Dormancy. Current Progress and Future Outlook. 2024;25(13):7133. (Open in a new window)Google Scholar Todd V, Johnso
NKs, considered nonspecific cytotoxic immune cells, are able to nonspecifically destroy infected abnormal cells (such as cancer cells) without prior activation or sensitization.75,76,77They generally express suppressive surface receptors, such as killer-cell immunoglobulin-like receptors (KIRs), that can...
Bone cancer prognosis has improved with advancements in early diagnosis and treatment options. Get information about types, symptoms, stages, and treatment of bone cancer.
Hematopoietic stem cell niche is a potential therapeutic target for bone metastatic tumors. Despite significant improvements in therapy, the prognosis for cancer with bone metastasis is generally poor. Therefore, there is a great need for new ther... Y Shiozawa,KJ Pienta,RS Taichman - 《Clinical...
and metastatic OS lesions. These studies have ultimately defined various cellular components and processes associated with therapeutic resistance, metastasis, and overall prognosis.19,20,21,22,23,24,25,26Researchers have also highlighted the presence of various immune escape mechanisms within the OS TME...
[2]. However, the existing treatment methodologies for these bone-related diseases have many problems, such as poor therapeutic effects and continued poor prognosis [3]. Intriguingly, some researchers have proposed using stem cell transplantation to treat bone-related diseases due to their ...
Jaffe N, Traggis D, Sallan S, Cassady R. Improved outlook for Ewing’s sarcoma with combination chemotherapy (vincristine, actinomycin D and cyclophosphamide) and radiation therapy. Cancer 1976; 38: 1925–30. PubMedGoogle Scholar Jaffe N, Murray J, Traggis D, Cassady JR, Filler RM, Watts...
The extracellular-regulated protein kinase 5 (ERK5) enhances metastatic burden in triple-negative breast cancer through focal adhesion protein kinase (FAK)-mediated regulation of cell adhesion. Oncogene 2021, 40, 3929–3941. [Google Scholar] [CrossRef] [PubMed] Liu, F.; Zhang, H.; Song, H....
Bone cancer represents one of the most significant causes of bone defects, with reserved prognosis regarding the effectiveness of treatments and survival rate. Modern therapies, such as hyperthermia, immunotherapy, targeted therapy, and magnetic therapy, seem to bring hope for cancer treatment in ...
Additionally, energy-related metabolites such as lactate and glutamine are altered in bone cancer. These metabolites and pathways can be utilized to develop diagnosis, prognosis, and treatment procedures of bone diseases. 3.1. Osteoporosis Osteoporosis (OP) is the most known and common bone disease....