NSCLC patients with bone metastasis showed a one-year survival rate of 40–50% [22]. Bone metastasis screening in patients with NSCLC is important for treatment decisions. To date, the mechanism of bone metastasis in lung cancer remains to be elucidated. Seed-soil theory is widely accepted [...
When patients have early-stage breast cancer without metastasis, their 5-year survival rate is as high as 90%, and once metastasis occurs, their 5-year survival rate will drop to 10%.3 Bone radionuclide imaging (ECT), X-ray, CT scan, MRI and other imaging tests to diagnose breast ...
A Case of Triple Early Gastric Cancer with Bone Marrow Metastasis The clinical outcome of early gastric cancer (EGC) has gradually been improving, and the 5-year survival rate for patients with EGC has been reported to ex... HJ Kim,BH Kim,BY Yoon,... - 《Korean Journal of Medicine》 ...
Breast cancer frequently metastasizes to the skeleton, interrupting the normal bone remodeling process and causing bone degradation. Osteolytic lesions are the end result of osteoclast activity; however, osteoclast differentiation and activation are mediated by osteoblast production of RANKL (receptor activat...
Bone cancer Oncogenes This article is cited by Retraction Note: Fibulin-3 knockdown inhibits cervical cancer cell growth and metastasis in vitro and in vivo Juan Li Chen Qi Min Shi Scientific Reports (2023) Rho-GEF Trio regulates osteosarcoma progression and osteogenic differentiation through Rac...
Nuclear scintigraphy is a sensitive technique to detect bone metastasis. A whole-body bone scan or PET/CT imaging is recommended when metastatic bone cancer is suspected because it is common for multiple sites of metastasis to be present, even if the patient is symptomatic for only one bone. ...
53 The survival rates were higher for women diagnosed with breast cancer at age 50 and above and for women diagnosed with small cancers (size below 1.0 cm). For stage 1 breast cancer, women with a BRCA1 mutation had a 5-year survival of 82%, which is lower than that for the...
Polyamines affect proliferation, differentiation, migration and apoptosis of cells, indicating their potential as a target for cancer chemotherapy. Ornithine decarboxylase converts ornithine to putrescine and is the rate-limiting step in polyamine synthe
The Journal of Cancer Metastasis and Treatment, under the leadership of Executive Chief Editor Ciro Isidoro, is dedicated to the latest research on the etiology, mechanisms, and treatment of various cancers with a focus on metastasis. Research topics cov
Patients with sole bone metastasis did not have a more favourable survival rate than patients with bone and other systemic metastases (p=0.2938). Whether metastasis is the first manifestation of lung cancer or not, the occurrence of bone metastasis generally means a poor prognosis....