blood-brain barrierdileptdilept metabolitepeptide carriersExperiments on rats with measurements by HPLC - MS/MS showed that antipsychotic preparation dilept (N-caproyl-L-prolyl-L-tyrosine methyl ester) administered per os in doses of 40 and 200mg/kg crossed the blood-brain barrier and was ...
The main objective of this study was to assess the blood-brain barrier (BBB) permeability in periventricular areas of the normal mouse brain to test the hypothesis that the fragility of the BBB in periventricular areas may play a role in periventricular white matter lesions. Vascular permeability ...
The mechanisms affecting blood-brain barrier () permeability in a are not well defined. We sought to determine whether one bacterial species, , when inoculated into the brain, can cause the to become abnormally permeable before leukocytes begin migrating into the brain. was induced by inoculating ...
血脑屏障Blood-Brain Barrier 热度: heterogeneity of the blood-brain barrier(血脑屏障的异质性) 热度: 人工智能基础(第2版) x2d;高济 x2d;ai x2d;4 x2d;本 热度: 相关推荐 Fluoresceinisothiocyanate(FITC)-DextranExtravasationasa MeasureofBlood-BrainBarrierPermeability RekaNatarajan, DepartmentofPharmacology...
percussion (FP) brain injury, the MRI observation of the BBB permeability reveals the barrier breakdown within 12 h post trauma,14 but few studies have been performed to investigate the longer events, such as the changes over a 24-h period post trauma, of the barrier permeability with MRI. ...
Blood–brain barrier permeability in Alzheimer's disease: a case–control MRI study. Psychiatry Res. 171, 232–241 (2009). Article CAS PubMed Google Scholar Al-Bachari, S. MRI assessment of neurovascular changes in idiopathic Parkinson's disease. Thesis, Univ. Manchester (2016). Google ...
Quantification of the acute increases in blood-brain barrier (BBB) permeability that occur subsequent to experimental ischemic injury has been limited to single time-point, invasive methodologies. Although permeability can be qualitatively assessed to visualise regional changes during sequential studies on ...
Negative Correlation of CD34+ Cells with Blood–Brain Barrier Permeability following Traumatic Brain Injury in a Rat Model Objective TBI causes localized cerebral ischemia that, in turn, is accompanied by both changes in BBB permeability and recruitment of CD34+ cells to the in... X Jin,F Wang...
A blood–brain barrier (BBB) opening induced by focused ultrasound (FUS) has been widely studied as an effective way of treating brain diseases. We investigate the effect of ultrasound’s incidence angle at caudate putamen (Cp) and thalamus (Th) of the r
103Junction adhesion molecules mediate the early attachment in the BBB developmental processes.104,105Kinase-like proteins modulate the blood–brain barrier permeability.106Interactions among these proteins provide physical support for the complex of tight junctions.107Downregulation of tight junction-related ...