Correlation heatmap: we used pearson’s correlation analysis to investigate the associations between potential biomarkers related to aging and constipation. Correlation coefficients (r) ranged from − 1.0 to 1.0, with 0 indicating no correlation. We presented the results using a cross-correlation ...
The study suggests a positive association between in utero drought exposure and faster biological aging in children in a global climate change hot spot. Drought experienced during pregnancy may reduce life expectancy. Xi Qiao ,Bilinda Straight
2,3]. Measures of aging biology have been proposed as a proxy to the global aging status of an individual [4]. Different tissues are commonly used, including saliva and blood derivatives, to measure biological aging. Blood tissues used include venous versus capillary and whole blood...
This aspect could also have important implications in terms of reduced health care costs, considering that the incidence of OP is expected to significantly enhance over the next decades due to the increase in life expectancy [57]. Furthermore, the idea of using blood biomarker panels alone and/...
2. The aging skeletal muscle and bone homeostasis 3. Cellular senescence 4. Senescence in the aging musculoskeletal apparatus 5. Nutrition, lifestyle, and musculoskeletal senescence 6. Conclusions and future perspectives Funding CRediT authorship contribution statement Declaration of Competing Interest Referen...
Identifying specific biomarkers conducive to exceptional survival might provide insights into counter-regulatory mechanisms against aging-related disease. Here, we report associations between cardiovascular disease-related biomarkers and survival to the highest ages using a unique dataset of...
Investigation of genetic variants and causal biomarkers associated with brain aging ArticleOpen access27 January 2023 The burden of rare protein-truncating genetic variants on human lifespan ArticleOpen access03 March 2022 Introduction Human lifespan is a highly variable and heterogeneous trait1. Until ...
Quantification of biological age as a determinant of age-related diseases in the Rotterdam Study: a structural equation modeling approach Article 13 April 2019 Clinical biomarker-based biological aging and risk of cancer in the UK Biobank Article Open access 29 April 2023 Introduction...
Environmental change has been shown to influence mammalian distribution, habitat use, and behavior; however, few studies have investigated the impact on physiological function. This study aimed to determine the influence of landscape condition on the exp
For incurable diseases, such as multiple sclerosis (MS), the prevention of progression and the preservation of quality of life play a crucial role over the entire therapy period. In MS, patients tend to become ill at a younger age and are so variable in terms of their disease course that ...