近日,《中国科学:生命科学》英文版(SCIENCE CHINA Life Sciences)以封面文章发表了由中国衰老标志物研究联合体(Aging Biomarker Consortium,ABC)六十余个研究组联合撰写的巨幅综述——Biomarkers of aging。该综述参考了逾 2 千篇衰老领域研究文献,以超 9 万字、31 张插图和 23 张表格的篇幅,系统总结了衰老标志物研...
National Institute on Aging (2023) Alzheimer’s disease fact sheet. National Institute on Aging. https://www.nia.nih.gov/health/alzheimers-and-dementia/alzheimers-disease-fact-sheet. Osipova D, Ahveninen J, Jensen O, Ylikoski A, Pekkonen E (2005) Altered generation of spontaneous oscillation...
To predict and prevent aging, biomarkers relevant to the aging process must be identified. This paper reviews the known molecular, cellular, and physiological biomarkers of aging. Moreover, we discuss the currently available technologies for identifying these biomarkers, and their a...
The search for biomarkers that quantify biological aging (particularly ‘omic’-based biomarkers) has intensified in recent years. Such biomarkers could predict aging-related outcomes and could serve as surrogate endpoints for the evaluation of intervent
Besides, the identification of biomarkers is complicated by the diversity of metabolic systems, lifestyle activities and medical treatments (1). Thus, there has been no single biomarker or gold standard tool that can accurately monitor healthy aging (2). The elderly often combine a variety of ...
IgA nephropathy (IgAN) has become the leading cause of end-stage renal disease in young adults. Nevertheless, the current diagnosis exclusively relies on invasive renal biopsy, and specific treatment is deficient. Thus, our study aims to identify potenti
Reproductive aging, spanning an age-related functional decline in the female and male reproductive systems, compromises fertility and leads to a range of health complications. In this Perspective, we first introduce a comprehensive framework for biomarke
Rosko:FDA ODAC Committee:Membership on an entity's Board of Directors or advisory committees;Sanofi:Research Funding.Wall:CTI:Speakers Bureau;Abbvie, BMS:H... AE Rosko,M Elsaid,SA Wall,... - 《Blood》 被引量: 0发表: 2023年 Molecular biomarkers of aging in the worm. Rosko:FDA ODAC Com...
Cited by (1) One-year longitudinal study of the stratum corneum proteome of retinol and all-trans-retinoic acid treated human skin: an orchestrated molecular event 2023, Scientific Reports© 2022 The Authors. Published by Elsevier, Inc. on behalf of the Society for Investigative Dermatology....
an expertconsensusduring the seminar held on March 12, 2023 at Tongji University, aiming to provide a basis for assessing the degree of brain aging and conducting brain-aging-related research with the ultimate goal of improving the brain health of elderly individuals in both China and the world...