The following elaborates how the formulated hypotheses may form the basis underlying palp choice during copulation. The hypotheses are grouped according to two ways a male spider may fill up its palps with sperm. First, mechanism A assumes that a random amount of sperm may be loaded into each ...
7 YAP fusions contain IDRs and form oligomers in the nucleus to promote tumorigenesis. a, Plot of disordered regions in YAP-C fusion identified using PONDR. VSL2 scores are shown on the y axis and positions are shown on the x axis. The blue bar designates the IDR investigated. b, Amino...
They should avoid introducing new facts in the form of unpublished data or personal communications. Thus, the reader will be able to assess the interpretations and evaluate the methodology employed in the publications that are cited in the review. The Introduction should outline the scope of the...
Opportunities for legitimate generative work form the core of the framework because it was our guiding definition of active-learning instruction and was woven throughout the thinking of our participants. Participants discussed this more than any other component and linked it directly to every other com...
[16] provides a set of general-purpose tools to work with genome graphs. Although VG is capable of mapping long reads to graphs, it was tuned for aligning short reads, leading to slow runtimes for long read alignment. In summary, there is presently a lack of general-purpose tools for ...
DNA methylation and histone modifications coexist in the genome and interact with each other to form a complex code for chromatin regulation and transcription. This and previous studies [32] revealed that the connections between DNA methylation and H3K9 methylation are extensive but vary widely in dif...
BMC Research Notes volume 5, Article number: 258 (2012) Cite this article 5560 Accesses 24 Citations Metrics details Abstract Background Saccharomyces cerevisiae senses hyperosmotic conditions via the HOG signaling network that activates the stress-activated protein kinase, Hog1, and modulates metabolic...
The axonemal microtubules of primary cilium undergo a conserved protein posttranslational modification (PTM) — polyglutamylation. This reversible procedure is processed by tubulin tyrosine ligase-like polyglutamylases to form secondary polyglutamate sid
We designed a multi-task deep learning model to simultaneously predict the TME classes and disease-free survival (DFS) from CT images. In multi-task learning, multiple tasks are simultaneously learned by a single model. Intuitively, it can be viewed as a form of inductive transfer, which cause...
Author notes Vasileios I. Floros and Angela Pyle contributed equally to this work. Authors and Affiliations MRC-Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK Vasileios I. Floros, Wei Wei & Patrick F. Chinnery Department of Clinical Neurosciences, Cambridge Biomedical Campus, Univ...