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et al. INTS10–INTS13–INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module. Nat. Commun. 11, 3422 (2020). Article CAS PubMed PubMed Central Google Scholar Mascibroda, L. G. et al. INTS13 variants causing a recessive developmental ciliopathy ...
Finally, we studied examples of complexes containing IDPs/IDRs that adopt a stable structure upon binding. IDRs often bind through short linear motifs (SLiMs), recognizing folded domains driven by a few residues. The longer IDRs can contain arrays of SLiMs and can also form stable structures upo...
Download references Author information Author notes Earl W. Chilton II Present address: Texas Parks and Wildlife Department, Fisheries and Wildlife Division, Inland Fisheries Branch, 4200 Smith School Road, 78744, Austin, TX, USA Authors and Affiliations Texas Parks and Wildlife Department, Heart of ...
Author notes Bernhard Bein and Françoise D. Lima contributed equally to this work. Authors and Affiliations Division of Evolutionary Biology, Faculty of Biology II, Ludwig-Maximilians-Universität München, Grosshaderner Strasse 2, 82152, Planegg-Martinsried, Germany Bernhard Bein & Ricardo J. Per...
2a, Additional file 1: Figure S2a), which is the only gene within the TAD. This pMEI has a 10.4% AF, is in active chromatin regions, and does not form any loops with surrounding genes or their promoters. Fig. 2 Epigenetic and chromatin interactions near the candidate GSH sites in ...
The graphical abstract should summarize the contents of your article in a concise, pictorial form which is designed to capture the attention of a wide readership. A graphical abstract will help draw more attention to your online article and support readers in digesting your research. Some guidelines...
2. The next step consists of searching through the SBML files of the models. For example, the 'notes' fields are examined, as they usually contain some information describing the model elements to which they are attached. 3. Finally, because it is impractical for BioModels Database to dup...
YAP-MAMLD1 concentrates transcription factors and co-activators, including BRD4, MED1 and TEAD, in condensates while excluding transcriptional repressive PRC2, and induces long-range enhancer–promoter interactions that promote transcription and oncogenic programmes. Blocking condensate-mediated transcriptional...