Recent discoveries in stem cell and developmental biology have introduced a new era marked by the generation of in vitro models that recapitulate early mammalian development, providing unprecedented opportunities for extensive research in embryogenesis.
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Finally, we studied examples of complexes containing IDPs/IDRs that adopt a stable structure upon binding. IDRs often bind through short linear motifs (SLiMs), recognizing folded domains driven by a few residues. The longer IDRs can contain arrays of SLiMs and can also form stable structures upo...
Only the proximal region 17b and the distal region below 17a can form homologous pairing and thus recombine with their homologs. Regions spanning from '22a' to '17a' cannot recombine because of a large intrachromosomal inversion. Regions '8', '17a', and '17b' were derived from short arm ...
Author notes Bernhard Bein and Françoise D. Lima contributed equally to this work. Authors and Affiliations Division of Evolutionary Biology, Faculty of Biology II, Ludwig-Maximilians-Universität München, Grosshaderner Strasse 2, 82152, Planegg-Martinsried, Germany Bernhard Bein & Ricardo J. Per...
2a, Additional file 1: Figure S2a), which is the only gene within the TAD. This pMEI has a 10.4% AF, is in active chromatin regions, and does not form any loops with surrounding genes or their promoters. Fig. 2 Epigenetic and chromatin interactions near the candidate GSH sites in ...
et al. A systems biology analysis of long and short-term memories of osmotic stress adaptation in fungi. BMC Res Notes 5, 258 (2012). https://doi.org/10.1186/1756-0500-5-258 Download citation Received26 October 2011 Accepted25 May 2012 Published25 May 2012 DOIhttps://doi.org/10.1186/...
An allele is a variant form of a given gene. Individuals who are heterozygous for a certain gene carry two different alleles. Mechanisms of breakpoint origination remain a mystery, but the idea of genes playing the role of “solid” regions can be explained by the fact that their functionalit...
Notes A sociocultural perspective of learning is also referred to as a situative perspective. Alternatively, some refer to this as a participation perspective or metaphor (Sfard 1998; Mason 2007; Vosniadou 2007; Wegner and Nückles 2015). Notably, the contrast between a cognitive and sociocultural...
(Supplementary Fig.3). Each insertion appears to be in a form of short and long tappings and occur multiple times, where sperm transfer occurs54. Males also use their legs to beat the females’ abdomen which visibly acts as an enhancement for copulation approval by the female54. If the ...