The following elaborates how the formulated hypotheses may form the basis underlying palp choice during copulation. The hypotheses are grouped according to two ways a male spider may fill up its palps with sperm. First, mechanism A assumes that a random amount of sperm may be loaded into each ...
On binding to the IC, these proteins cause a major conformational change involving the movement of β-lobe/βi4 to form contacts with DksA (or TraR) (Fig. 4a), which widens the main channel of RNAP, thus facilitating a reversal of the open-promoter complex (RPo)22,23. This ...
(More information is available in Additional file 1: Supplemental Notes.) Milkweed bug strain, rearing, and DNA/RNA extraction The milkweed bug Oncopeltus fasciatus (Dallas), Carolina Biological Supply strain (Burlington, NC, USA), was maintained in a laboratory colony under standard husbandry co...
To inspect the possible cell surface-presentation of nuclear-encoded RNA, we developed a technology called Surface-seq. Surface-seq is based on a nanotechnology that extracts the plasma membrane from cells and tightly assembles the membrane around polymeric cores to form membrane-coated nanoparticles ...
Here, unexpectedly, we find that liquid–liquid phase separation, rather than nuclear localization, of recurrent patient-derived YAP fusions, YAP-MAMLD1 and C11ORF95-YAP, underlies ependymoma tumourigenesis from neural progenitor cells. Mutagenesis and chimaera assays demonstrate that an intrinsically ...
We designed a multi-task deep learning model to simultaneously predict the TME classes and disease-free survival (DFS) from CT images. In multi-task learning, multiple tasks are simultaneously learned by a single model. Intuitively, it can be viewed as a form of inductive transfer, which cause...
Review ReportsVersions Notes Abstract Past-oriented rumination and future-oriented worry are two aspects of perseverative negative thinking related to the neuroticism endophenotype and associated with depression and anxiety. Our present aim was to investigate the genomic background of these two aspects of...
Here, the dichotomous path was replaced by a polytomous algorithm which presents more than two characteristics of a plant feature to the user in the form of a graphic representation (Figure 1). For previously identified problems with the recognition of plant characteristics, explanatory videos are ...
Versions Notes Abstract Discovered over 40 years ago, the annexin proteins were found to be a structurally conserved subgroup of Ca2+-binding proteins. While the initial research on annexins focused on their signature feature of Ca2+-dependent binding to membranes, over the years the biennial Annex...
catalyzed pectin to form pectic acid; StproC27072 catalyzed L-1-pyrroline-5-carboxylic acid to form L-proline; 4. The intracellular accumulation of Ca2+and pectic acid formed pectin gel through bridging action; diacyl-sn-glycerol was further metabolized to form triglycerides; 5. The massive form...