Bile acids are central to enterohepatic signaling pathways activated through natural receptors, farnesoid X receptor [FXR mediates synthesis of fibroblast growth factor-19 (FGF-19)], and G protein-coupled bile acid receptor 1 (GPBAR1, also known as TGR5). Although bile acid diarrhea (BAD) is ...
Bile acid diarrhoea (BAD) is a commonly missed cause of chronic diarrhoea and has been demonstrated in excess of a quarter of patients who were previously diagnosed with IBS-D1,2. Functional bowel disorders such as IBS form the largest group of patients seen in a general gastroenterology clinic...
bile acid如何读 英:[baɪl ˈæsid] 美:[baɪl ˈæsɪd] bile acid是什么意思 胆汁酸 bile acid英英释义 noun any of several steroid acids (such as cholic acid) that occur in bile especially in the form of bile salts, are produced chiefly in the liver from cholesterol, and ...
coated with a polymer so as to allow the release thereof around the lower part of the small intestine and the cecum; and medicines (for example, antilipemics) comprising a combination of bile acid re-absorption inhibitors with the above-described preparations for preventing bile acid diarrhea.do...
Preparations for preventing bile acid diarrhea which comprise containing a bile acid adsorbent coated with a polymer so as to allow the release thereof around an area from the lower part of the small intestine to the cecum; and pharmaceutical compositions comprising a combination of bile acid re-...
Synthetic pathways of bile acids and enterohepatic bile acid circulation. LDL, low-density lipoprotein; LDLR, low-density lipoprotein receptor; NTCP, Na + -dependent taurocholic acid co-transporting polypeptide; OATP, organic anion-transporting polypeptides; BSEP, bile salt export pump; ASBT, apic...
actions in the colon. They are preferentially (95%) absorbed in the terminal ileum through enterohepatic circulation. Bile acid malabsorption or bile acid diarrhea occurs when reabsorption is impaired due to ileal disease or ileal resection and bile acidss stimulate water secretion and intestinal ...
actions in the colon. They are preferentially (95%) absorbed in the terminal ileum through enterohepatic circulation.Bile acid malabsorptionor bile acid diarrhea occurs when reabsorption is impaired due to ileal disease or ileal resection and bile acidss stimulate water secretion and intestinal motility...
Define Bile acid sequestrant. Bile acid sequestrant synonyms, Bile acid sequestrant pronunciation, Bile acid sequestrant translation, English dictionary definition of Bile acid sequestrant. n. A chemical that promotes sequestration. American Heritage®
23 In a few patients, the movement of the bile acid pool to the distal intestine seems to overwhelm the ileal transport system, and bile acid malabsorption occurs. This is clinically manifest as diarrhea and generally responds to administration of a bile acid sequestrant. Ileal Resection ...