Here, they produce Cl- secretion by a calcium- and cyclic AMP-dependent mechanism, resulting in diarrhea. Cholestasis may lead to serum bile acid concentrations high enough to produce colonic secretion by serosal surface effects. When resection or disease interferes with ileal function, the ...
Although bile is not as strong an irritant as acid, it can still cause ongoing inflammation of both the stomach and esophageal lining. Changes of pH and the presence of theHelicobacter pylori(H.pylori) bacterium can alter the composition of the bile rendering it into different forms, all of ...
Preparations for preventing bile acid diarrheaPreparations for preventing bile acid diarrhea characterized by containing a bile acid adsorbent coated with a polymer so as to allow the release thereof around the lower part of the small intestine and the cecum; and medicines (for example, antilipemic...
Bile Acid Malabsorption Caused by Ileal Resection Two syndromes of bile acid malabsorption caused by ileal resection—bile acid diarrhea (cholerheic diarrhea) and fatty acid diarrhea (steatorrheic diarrhea)—have been identified, characterized, and symptomatic therapy has been developed... AF Hofmann ...
Diarrhea: Impaired feedback inhibition of bile acid synthesis associated with bile acid diarrheaPurpose: Intensity modulated radiation therapy (IMRT) is a significant therapeutic advance in prostate cancer, allowing increased tumor dose delivery and increased sparing of normal tissues. IMRT planning uses ...
Preparations for preventing bile acid diarrhea which comprise containing a bile acid adsorbent coated with a polymer so as to allow the release thereof around an area from the lower part of the small intestine to the cecum; and pharmaceutical compositions comprising a combination of bile acid re-...
(lipoproteins anchored to the periplasmic face), outer membrane proteins BepA and YfgM, and MipA, DacA, and DacC (involved in peptidoglycan biosynthesis and structure). In addition, NaGCH upregulated the amino acid uptake/transport proteins GlnQ, GltL, PheA, and PutP (Fig.2, Supplementary ...
Na+-dependent bile acid transport in the ileum: The balance between diarrhea and constipation AJP, De Rooij FWM, Van Blankenstein M, et al: Naϩ- dependent bile acid transport in the ileum: The balance between diarrhea and constipation. Gastro... AJP Van Tilburg,FWM De Rooij,M Van ...
tu1262 obeticholic acid, a farnesoid x receptor agonist, reduces bile acid synthesis in patients with primary bile acid diarrhea-tu1262 obeticholic酸,法尼酯X受体激动剂,降低了胆汁酸合成原发性胆汁酸腹泻-知来论文发表中心DOI: 10.1016/S0016-5085(14)62881-X 被...
OBJECTIVETo determine the best possible treatment for two brothers who had IDDM and bile acid malabsorption-associated disabling diarrhea that was resistant to cholestyramine, antibiotics, clonidine, loperamide, or anticholinergic drugs.RESEARCH DESIGN AND METHODSOur study paired these two brothers with cont...