This document is a comment on a recent review article about bile acid diarrhea (BAD) and its molecular mechanisms. The authors of the comment agree with the review's discussion of key components of bile acid metabolism and the current diagnostic methods for BAD. However, they argue that the ...
A Clostridia-rich microbiota enhances bile acid excretion in diarrhea-predominant irritable bowel syndrome. J. Clin. Invest. 130, 438–450 (2020). Article CAS PubMed Google Scholar Bárcena, C. et al. Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice. Nat...
Here, we review current knowledge on the intersections and shared signaling pathways associated with diarrhea﹑redominant irritable bowel syndrome, bile acid diarrhea, and NAFLD. These signaling pathways are centered on disturbed enterohepatic bile acid homeostasis, and in particular, ileal enterokine ...
Your doctor will decide if you need to discontinue treatment with CHOLBAM. Most Common Side Effects: Diarrhea, acid reflux that damages the lining of the esophagus, discomfort and fatigue, yellowing of skin or eyes, skin lesion, nausea, abdominal pain, formation of growths in the intestinal ...
Surgical resection of the small bowel, especially the ilium, disrupts the enterohepatic circulation of bile acids, resulting in their excess concentration in the colon, which manifests itself as diarrhea. Bile acid supplementation has therapeutic value in several conditions, such as primary biliary ...
Bile acid diarrhea. 来自 EBSCO 喜欢 0 阅读量: 62 作者:Potter,D Gregory 摘要: Bile acids normally undergo enterohepatic circulation. When this circulation is interrupted, bile acids enter the colon in increased concentrations. Here, they produce Cl– secretion by a calcium- and cyclic AMP-...
In conclusion, gut microbiota dysbiosis induced by a humid heat environment drives the progression of anxiety disorders by impairing bile acid metabolism and enhancing neuroinflammation, and probiotic administration is a potential therapeutic strategy for these disorders....
Sign up with one click: Facebook Twitter Google Share on Facebook sequestrant (redirected fromBile acid sequestrant) Medical Acronyms Wikipedia se·ques·trant (sĭ-kwĕs′trənt) n. A chemical that promotes sequestration. American Heritage® Dictionary of the English Language, Fifth Edition...
Purpose of review Bile acid diarrhea (BAD) is a common but under-recognized gastrointestinal condition that manifests with increased stool frequency and urgency, and a looser stool consistency. The aim of this review is to present recent advances in the pathophysiology, mechanisms, manifestations, di...
The gut microbiota-bile acid axis as a target for CLD treatment FXR ligands Current studies have provided substantial evidence that multiple FXR agonists could ameliorate the gut microbiota, suppress BA synthesis and metabolism, and relieve liver fibrosis progression in animal models with cholestasis (...