Al-Saqladi AW, Brabin BJ, Bin-Gadeem HA, Kanhai WA, Phylipsen M, Harteveld CL. Beta-globin gene cluster haplotypes in Yemeni children with sickle cell disease. Acta Haematol. 2010; 123 :182–5.Al-Saqladi AW, Brabin BJ, Bin-Gadeem HA et al (2010) Beta-globin gene cluster ...
We have studied the transient expression of a cloned rabbit hemoglobin β1 gene after its introduction into HeLa cells. Two and one-half days after transfection using the calcium phosphate technique, we extracted RNA from the entire cell population and analyzed it by the S1 nuclease hybridization ...
The beta-globin gene cluster is located on chromosome 11. SNPs database was published by Hap Map Project. Here, novel tag SNPs on beta -globin gene cluster in Chinese Han population was reported on using Haploview 4.2. The haplotype block and LD analysis showed three blocks that were ...
Sardinian delta beta 0-thalassemia is an inherited syndrome characterized by the inactivity of the beta-globin gene and the persistent activity of the fetal gamma-globin genes, particularly the A gamma-globin gene. Previous mapping studies with restriction enzymes failed to show any abnormality in th...
doi:10.4274/jpr.37450GENETIC polymorphism researchHEMOGLOBINSA letter to the editor is presented which discusses a polymorphism of a novel beta globin gene in Turkish population.Journal of Pediatric ResearchAkar, NejatCeylaner, SerdarDoan, Haldun...
NF-E2 is one of the key transcription factors in beta-globin gene transcriptional activation. To shed light on whether NF-E2 is involved in this process, DS19MafKsiRNA cell pools were established by specifically knocked down the expression of MafK/NF-E2 p18, one subunit of NF-E2 heterodimer....
A retroviral vector containing a 4.4-kb Pst I human beta S-globin gene and a neomycin resistance gene was used to infect NIH-3T3 and mouse erythroleukemia cells (MELC). In MELC, human beta-globin mRNA transcripts are transcribed and properly initiated and spliced. In some cases, there is...
Human beta-globin gene expression appeared to be restricted to cells of the erythroid lineage and was first detected between 11 and 14 days of development, in parallel with mouse beta-globin. Constructs with as little as 48 bp of 5'-flanking sequence also appeared to be expressed appropriately...
Nonsense mutations in the human beta-globin gene affect mRNA metabolism. Baserga;SJ;Benz;EJ;Jr.Nonsense mutations in the human beta-globin gene affect mRNA metabolism.0.2056-2060Baserga SJ, Benz EJ Jr (1988) Nonsense ... S,J,Baserga,... - 《Proceedings of the National Academy of ...
To assess the relationship between being beta globin gene carrier and developing insulin resistance.This study was conducted on 164 subjects including 82 healthy ones and 82 patients with beta thalassemia minor (microcytosis (MCV <80 fl) and hypochromia (MCH <25 pg) and HbA2 ≥ 3.5% using HP...