If the mutations in these 尾-globin gene haplotypes, such as the mutation described in this study, are responsible for the protective effects seen in patients, perhaps some of these genetic locations can serve as targets for therapeutics in sickle cell disease or other blood disorders.Gesiotto, ...
However, 200 times more β-globin gene transcripts were found when the β-globin gene recombinants also contained SV40 DNA, and 90% of these transcripts (about 1000 per cell) had the same 5′ end as authentic rabbit globin mRNA. In the latter case, abundant production of β-globin protein...
Sardinian delta beta 0-thalassemia is an inherited syndrome characterized by the inactivity of the beta-globin gene and the persistent activity of the fetal gamma-globin genes, particularly the A gamma-globin gene. Previous mapping studies with restriction enzymes failed to show any abnormality in th...
The beta-globin gene cluster is located on chromosome 11. SNPs database was published by Hap Map Project. Here, novel tag SNPs on beta -globin gene cluster in Chinese Han population was reported on using Haploview 4.2. The haplotype block and LD analysis showed three blocks that were ...
网络类β珠蛋白基因簇 网络释义 1. 类β珠蛋白基因簇 gene-英汉词典... ...beta like globin gene cluster[医]类β珠蛋白基因簇bithorax comples gene [医]果蝇的双胸复合基因 ... www.fastdict.net|基于 1 个网页
Identification and characterization of adult alpha-and beta-globin genes and their genomic arrangement in Pseudosciaena crocea65阅读 文档大小:376.33K 12页 lujiudui1996上传于2015-06-15 格式:PDF Association of tnf alpha and tnf beta gene polymorphisms with primary open angle and primary angle closure ...
(The codon at which the mutation occurs designates the name of the mutation; there are 146 codons in human β -globin mRNA.) In vitro studies using the cloned β -39 gene have reproduced this effect in a heterologous transfection system and have suggested that the defect resides in ...
IVSII-666 of human beta-globin gene: a polymorphic marker linked to codon 8(-AA) mutation. 来自 NCBI 喜欢 0 阅读量: 49 作者: Akhavan-Niaki, Haleh, Seresti, Siamak Shafiezadeh, Asghari, Beheshteh, Banihashemi, Ali 摘要: AIMS: IVSII-666 (C-T) is one of the polymorphic sites ...
Vertebrate alpha (α)- and beta (β)-globin gene families exemplify the way in which genomes evolve to produce functional complexity. From tandem duplication of a single globin locus, the α- and β-globin clusters expanded, and then were separated onto
1. High-mobility group protein 2 may be involved in the locus control region regulation of the beta-globin gene cluster [J] . Lv X, Xu DD, Liu DP, Biochemistry and Cell Biology . 2002,第6期 机译:高迁移率族蛋白2可能参与β-珠蛋白基因簇的基因座控制区调控 2. Beta-globin gene swit...