Scharfmann Lab The EndoC βH cell lines represent powerful tools to study functional human beta cells. We have produced 3 generations of the EndoC βH cell line used by over 150 research groups across the world. Scharfmann, R., Staels, W., & Albagli, O. The supply chain of human pa...
Significant permeability of in vitro human chorion laeve to glucose, glycerol, and beta-hydroxybutyrate (betaOH butyrate) and in vitro sheep chorion leave to glycerol and betaOH butyrate was measured. Diffusion across these tissues of glycerol and betaOH butyrate corresponded to the relative molecular...
In vitro studies show that Il-3 and GM-CSF caused a 2–4-fold increase in F-cells and γ-globin chains, but that c-kit ligand is associated with a 20-fold increase, which is enhanced further by the addition of sodium butyrate [46]. The effect of c-kit on F-cells is accompanie...
Substituted adamantanes of general formula (35) can be (a) treated with trifluoroacetic anhydride in a solvent like trifluoroacetic acid; and (b) treating the product of step (a) with a thiol of formula R101SH at elevated temperature, typically at about 120° C. for a period of about 20...
Induction of HbF synthesis can reduce the severity of beta-thalassemia by improving the imbalance between alpha and non-alpha globin chains. Several compounds including 5-azacytidine, decytabine, and butyrate derivatives gave encouraging results in clinical trials [87]. These agents induce Hb F by ...
Induction of HbF synthesis can reduce the severity of beta-thalassemia by improving the imbalance between alpha and non-alpha globin chains. Several compounds including 5-azacytidine, decytabine, and butyrate derivatives gave encouraging results in clinical trials [87]. These agents induce Hb F by ...
The prevalence and incidence of metabolic syndrome is reaching pandemic proportions worldwide, thus warranting an intensive search for novel preventive and treatment strategies. Recent studies have identified a number of soluble factors secreted by adipo
Adamus, G. Molecular Level Structure of (R,S)-3-Hydroxybutyrate/(R,S)-3-Hydroxy-4-ethoxybutyrate Copolyesters with Dissimilar Architecture.Macromolecules2009,42, 4547–4557. [Google Scholar] [CrossRef] Adamus, G.; Sikorska, W.; Janeczek, H.; Kwiecień, M.; Sobota, M.; Kowalczuk, M....
Additionally, targeted metabolites analysis revealed an elevated level of cecal short-chain fatty acids (SCFAs) including acetate, propionate, and butyrate [48]. Supplementation of SCFAs has been increasingly known for its potential to alleviate hepatic steatosis and inflammation in rodents [67]. An ...