TEM-1 beta-lactamase is the most widespread enzyme to confer beta-lactam antibiotic resistance to gram-negative bacteria. It is a monomeric protein that requires no metals or cofactors for activity. TEM-1 beta-lactamase efficiently hydrolyzes most penicillin and cephalosporin substrates, including nit...
especially with the emergence of the TEM-1 enzyme, a β-lactamase that has an active site ideally suited to hydrolysing this antibiotic. This is the most common resistance mechanism to any antibiotic and, in some areas, 25% of the population carry the gene in their commensal bacteria. In ...
Introduction Objective: TEM-1 beta lactamase gene is one of the important plasmidic genes in Enterobacteriaceae which is the cause of over 90% of Escherichia coli isolates resistance to beta lactam antibiotics. In this study, the frequency of TEM-1 gene in nosocomial strains of Escherichia coli,...
Beta Lactamase E.coli Recombinant ENZ-351 1mg ($145) 10mg ($990) 50mg ($4000) Shipped at Room temp. Catalogue number ENZ-351 Synonyms b-Lactamase, EC 3.5.2.6, TEM-1. Introduction Beta-lactamase is a type of enzyme (EC 3.5.2.6) produced by some bacteria that is responsible for...
提供的Beta-lactamase单克隆抗体,克隆号8A5。A10是从小鼠体内制备的单克隆抗体,其克隆号为8A5。A10。 应用类型 WB,ELISA 免疫原 5'-His-tagged TEM-1 beta-lactamase。 来源宿主 小鼠 反应性 大肠杆菌 保存建议 置于-20度温度保存,分装以避免反复冻融。
英文别名: beta-lactamase TEM-1 中文名: 中文别名: CBNumber: CB91328870 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 0 beta-lactamase TEM-1化学性质 安全信息beta-lactamase TEM-1性质、用途与生产工艺 beta-lactamase TEM-1 上下游产品信息 上游原料 下游产品beta-lactamase ...
The crystal structure of the TEM1 β-lactamase has been determined at 1.9Å resolution by the molecular-replacement method, using the atomic coordinates of two homologous β-lactamase refined structures which show about 36% strict identity in their amino-acid sequences and 1.96Å r.m...
It was found that BLIP has significant differences in binding affinities toward TEM-1 and SHV-1 beta-lactamases. 展开 关键词: Binding Free Energy TEM-1 beta-lactamase SHV-1 beta-lactamase BLIP Molecular Dynamics 会议时间: 03 June 2010 被引量: 6 ...
Interestingly, the protein crystallization agent 6-cyclohexyl-hexyl-β-D-maltoside (CYMAL-6) also inserts into the same site in a closely related class A beta-lactamase, SHV-1 [16]. Here, we first investigated the inhibition of TEM-1 by CYMAL-6 through binding this allosteric site. Then ...
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