beta-lactam beta-lactamase See More Nearby Entries Cite this Entry Style “Beta-lactam.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/beta-lactam. Accessed 9 Dec. 2024. Copy Citation Share...
beta-lactamantimicrobial resistancecarbapenemaseenzyme mechanismThe beta-lactams retain a central place in the antibacterial armamentarium. In Gram-negative bacteria, beta-lactamase enzymes that hydrolyze the amide bond of the four-membered beta-lactam ring are the primary resistance mechanism, with multiple...
Amoxicillin, an oral beta-lactam, is effective for susceptible strains of S. pneumoniae and, when used at high doses (3 to 4 grams per day), is effective against 90 to 95% of S. pneumoniae strains. Concomitant use of a beta-lactamase inhibitor (clavulanate) extends the spectrum of ...
Beta-Lactamase Inhibitor Screening Kit 产品编号:3413917 产品类别:试剂盒 纯度规格:Sufficient for 100 Colorimetric tests 包装规格:1 KIT 市场价:8980元 优惠价:立即咨询 β-内酰胺酶抑制剂筛选试剂盒 Beta-Lactamase Inhibitor Screening Kit β-Lactamase Inhibitor Screening Kit ...
(redirected fromBeta-lactam antibiotics) Medical Encyclopedia Related to Beta-lactam antibiotics:beta-lactamase,Aminoglycosides n. Any of a class of broad-spectrum antibiotics, such as the penicillins and the cephalosporins, that contain a beta-lactam ring. ...
BETA-LACTAMASE: The capacity to produce beta-lactamase, an enzyme which hydrolyses penicillin and cephalosporines, is the main source of bacterial resistance to beta-lactamines, thus the important contribution of beta-lactamase inhibitors (clavanulanic acid, sulbactam and tazobactam). MECHANISM OF ACTI...
beta-lactamase (redirected fromBeta lactamase) Thesaurus Medical Encyclopedia be·ta-lac·ta·mase (bā′tə-lăk′tə-mās′, -māz′, bē′-) n. Any of various enzymes that hydrolyze and inactivate beta-lactam antibiotics such as penicillin, found in many antibiotic-resistant bacteria. ...
A novel beta-lactamase inhibitor has been isolated from Streptomyces clavuligerus ATCC 27064 and given the name clavulanic acid. Conditions for the cultiva... C Reading,M Cole - 《Antimicrob Agents Chemother》 被引量: 1051发表: 1977年 Monotherapy versus beta-lactam-aminoglycoside combination treatment...
Piperacillin‐Tazobactam: A New β‐Lactam‐β‐Lactamase Inhibitor Combination We reviewed the spectrum of activity, pharmacokinetics, clinical efficacy, adverse effects, and relative advantages of piperacillin-tazobactam, a new β-la... Karen P. Daniel,Lynne C. Krop - 《Pharmacotherapy the Journal ...
especially since KPC-producing strains are typically resistant to aminoglycosides and fluoroquinolones, leaving few therapeutic options.59KPC-type beta-lactamases are inhibited by clavulanic acid and tazobactam, but isolates expressing KPC can be resistant to beta-lactamase inhibitor/beta-lactam combinations ...