To provide theoretical basis for BDNF gene therapy of exercise-induced SCI by analysis of physiological characteristics of BDNF and its receptor,pathological features of exercise-induced SCI.% 目前,有关运动性脊髓损伤的研究尚不充分,而且对其损伤机制和治疗方法也没有取得较好的研究进展.随着研究的深入,发现...
et al. BDNF gene therapy induces auditory nerve survival and fiber sprouting in deaf Pou4f3 mutant mice. Sci. Rep. 2, 838; DOI:10.1038/srep00838 (2012). SCIENTIFIC REPORTS | 2 : 838 | DOI: 10.1038/srep00838 9 http-equiv="content-type" ...
脑源性EPO的发现和研究,为探讨脑缺血耐受机制提供了新的视角,也为脑缺血的防治提供了新的启示。 4) brain derived 脑源性 1. Objective: To observe the value of gene therapy on SCI in vivo by transferringbrain derivedneurotrophic factor (BDNF) to rat myoblast with retroviral vector using electrophysiol...
The discovery of an estrogen response element- (ERE-) like motif in the BDNF gene promotor region provides a possible mechanism through which estradiol is able to directly regulate BDNF expression [10]. Investigating the Interactive Effects of Sex Steroid Hormones and Brain-Derived Neurotrophic Factor...
脑源性神经营养因子_BDNF_与运动性脊髓损伤
Mouse models are useful for studying genes involved in behavior, but whether they are relevant for human behavior is unclear. Here, we identified parallel phenotypes in mice and humans resulting from a common single-nucleotide polymorphism in the brain-derived neurotrophic factor (BDNF) gene, which...
3.The Effect of Gene Clone and Gene Engineering Cells of Brain-derived Neurotrophic Factor (BDNF) on Brain Slice in Vitro;脑源性神经营养因子(BDNF)基因克隆及其基因工程细胞对体外培养脑片生长的影响 4.Adenovirally Delivered BDNF to Murine Ocular Tissues Hepls Improve the Repairment of Crushed Optic ...
In our study, only three patients had previous surgical therapy for endometriosis. Most of the patients were initially diagnosed with endometriosis in our hospital and underwent surgery because they had no significant symptomatic improvement after pharmacological treatment. It is also noteworthy that ...
In Vivo Gene Therapy for Sciatic Nerve Injury of Adult Rats by Adenovirus-mediated Gene Transfer of BDNF; 腺病毒介导的BDNF基因转移治疗大鼠坐骨神经损伤 9. Effects of Adenovirus-mediated BDNF Gene Transfer into Spinal Cord to Treat Nerve Root Injury and Its Mechanism; 腺病毒介导的BDNF基因脊髓内...
phicfactor 脑源性神经营养因子 cDNA complementaqrDNA 互补DNA COMT transferase 儿茶酚0_甲基转移酶 catechol-O-methyl CREB cAMP ement cAMP反应性元件结合蛋白 responseelbindingprotein 质 dopamine 多巴胺 DeoxynbonucleBacid 脱氧核糖核酸 electroconvulsive 电抽搐治疗 therapy kinase extracellularsignal—reg—ulated...