The ratio of antagonists of apoptosis, such as Bcl-2, to agonists, such as Bax, is thought to determine the outcome for a particular cell. This study aimed to determine the expression of Bcl-2 and Bax proteins in a series of oligodendrogliomas and to relate the expression of these to ...
Killing cancer cells by flipping the Bcl-2/Bax switch. Cancer Cell. 2005 Jul;8(1):5-6. [5] Xiao D, Zhang L. Upregulation of Bax and Bcl-2 following prenatal cocaine exposure induces apoptosis in fetal rat brain. Int J Med Sci. 2008;5(6):295-302. [6] Alam M, Alam S, ...
bcI-2蛋白表达与凋亡阳性细胞数呈负相关(r= 0.781,P<0.05),bax蛋白表达与其呈正相关(r=0.723,P<0.05)。结论:出血灶周围脑组织中存在细胞凋亡,细胞凋亡的变化在一定程度上反映了周围脑组织的损伤程度。bcI-2和bax蛋白对凋亡具有调控作用。ApoptosisandexpressionsofbcI-2andbaxproteininperihematomaIbrainregionsof...
1、Bax 中文:BCL2-Associated X的蛋白质。英文:BCL2-Associated X。释义:属于兔抗人单克隆抗体。2、bcl-2 中文:B淋巴细胞瘤-2基因。英文:B-cell lymphoma-2。释义:细胞凋亡研究中最受重视的癌基因之一。
Bax对Bcl-2的抑凋亡功能有对抗调节作用,二者共同决定细胞是否走向凋亡关键字:胃癌癌前病变基因蛋白凋亡TheexpressionofBcl-2andBaxproteinandrelatiohipbetweenthemandapoptosisingastriccarcinomaandprecancerouslesio【Abstract】ObjectiveTostudytheexpressionofBcl-2andBaxproteinandexploretherelatiohipbetweenthemandapoptosisin...
TSRP通过在体内和体外抑制Bcl-2、Fas表达,增加Bax表达诱导Raji细胞凋亡。此外,TSRP对控制体外细胞凋亡的线粒体途径有一定的影响。 扫码二维码获取全文 引用格式 Xu XF, Cheng RB, Zhang XJ, Gao RL. Total saponins in Rubus parvifolius L.induce lymphoma cells apoptosis through upregulated Bax/Fas and downr...
Involvement of Bcl-2 and Bax in Photodynamic Therapy-mediated Apoptosis. Antisense Bcl-2 oligonucleotide sensitizes RIF 1 cells to photodynamic therapy apo... Involvement of BCL- 2 and Bax in Photodynamic Therapy-mediated Apoptosis: ANTISENSE BCL-2 oligonucleotide sensitizes rill cells to photodynamic ...
Apoptosis regulator proteins bcl-2 and bax were measured in all patients using alkaline phosphatase anti-alkaline phosphatase method. Twenty-one patients were positive for bcl-2 and 23 cases for Bax, although expression levels varied. Patients who presented with splenomegaly or hepatomegaly <5 cm ...
These results demonstrate a significant role of hepatocellular apoptotic processes in the later development of necrosis in the liver. The kientics of this apoptosis are directly proportionate to the disturbed ratio of Bcl-2 and Bax. 展开 关键词: endotoxin shock hepatocellular apoptosis Bcl-2 Bax ...
抗凋亡蛋白(如BCL-2、BCL-XL、BCL-W、MCL-1、BFL-1/A1);促凋亡孔形成蛋白(如BAX、BAK、BOK)...