cleaved form of c-FLIP long form [c-FLIP(L)]–p43 at theDISCprevents caspase-8 cleavage[45]. In addition, high expression of X-linked inhibitor of apoptosis protein (XIAP) induces TRAIL resistance[46]. Mutation in the proapoptoticprotein Baxhas been shown to contribute to TRAIL resistance ...
别名:Beclin-1; ATG6; beclin1; VPS30; Beclin 1 like protein 1; 4921513J16Rik; 5430417M23Rik; ATG6; BECLIN 1; BECN1; MGC6843; BECN1_HUMAN. 研究领域 :免疫学 神经生物学 细胞凋亡 抗体来源 :Mouse *类型 :Monoclonal 克隆号 :7D7
apoptosis B-cell lymphoma 2 (Bcl-2) family fusion protein leukemia tyrosine-protein kinase (tyrosine kinase) Recurrent fusion genes in acute lymphoblastic leukemia Acute lymphoblastic leukemia (ALL)2 is the most common form of childhood malignancy. Therapy for ALL is one of the great success storie...
Alterations in Bcl-2/Bax protein levels in platelets form part of an ionomycin-induced process that resembles apoptosis. Br J Haematol. 1997;99:824 -31.Vanage;DM;Orrenius;S;Aguilar-Santelises;M.Alterations in Bcl-2/Bax protein levels in platelets from part of an ionomycin-induced process ...
Full size table Current evidence for a role of BCL2β Despite the accumulation of evidence for the many roles of BCL-2α, there has been very little investigation into the role of BCL-2β. Functional protein studies on BCL-2 primarily focuses on the wildtype BCL-2α. Where the BCL-2β...
Although a wealth of knowledge has been gained from cell-free assays, there still remains the possibility that other features, such as conformational changes that might already be occurring before translocation or exchange equilibrium between membrane bound and cytosolic form of the protein, can be ...
In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative. Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends. The overexpression of BCL-2 has...
Protein degradation, resulting from frozen storage, reduced the digestive efficiency of the pork proteins. The samples, frozen at high temperatures and stored for a long duration, exhibited a more substantial demonstration of this phenomenon.For an alternative cancer treatment approach, the combination ...
Full length protein 无动物成分 No 性质 Recombinant 种属 Human 序列 MGSSHHHHHH SSGLVPRGSH MGSHMAKQPS DVSSECDREG RQLQPAERPP QLRPGAPTSL QTEPQDRSPA PMSCDKSTQT PSPPCQAFNH YLSAMASMRQ AEPADMRPEI WIAQELRRIG DEFNAYYARR VFLNNYQAAE DHPRMVILRL LRYIVRLVWR MH ...
Cited in 938 publications. Bcl2 antibody for WB, IHC, IF/ICC, FC (Intra), ELISA and reacts with mouse, rat.