Bcl2 Polyclonal Antibody for WB, IHC, IF/ICC, FC (Intra), ELISA Cat No. 26593-1-AP 引用文献(975) 宿主/亚型 Rabbit / IgG 种属反应性 mouse, rat and More (6) 应用 WB, IHC, IF/ICC, FC (Intra), ELISA and More (2) 别名 Bcl-2, Bcl 2, B cell leukemia/lymphoma 2 缓冲...
Full Name B-cell CLL/lymphoma 2 Calculated Molecular Weight 26 kDa Observed Molecular Weight 25-30 kDa GenBank Accession Number BC027258 Gene Symbol BCL2 Gene ID (NCBI) 596 RRID AB_2227948 Conjugate Unconjugated Form Liquid Purification Method Antigen affinity purification UNIPROT ID P10415 Storag...
Bcl2样蛋白11(BCL2L11)重组蛋白 种属: Homo sapiens (Human) 蛋白长度: Full Length 来源: E.coli 分子量: 26.2 kDa 表达区域: 1-198aa 氨基酸序列 MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQ
Recombinant protein corresponding to full-length human BCL2. Reactivity Human Form Liquid Purification Protein A/G purification Isotype IgG Recommend Usage Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL) Western Blot (1-2 ug/mL) ...
From early studies employing immunoprecipitation and yeast two-hybrid analysis it was noted that the Bcl-2 family of proteins form homodimers and heterodimers and it was suggested this was important for function (Oltvai et al., 1993; Yang et al., 1995). However, more recently Bcl-2 family ...
43, 44 It is tantalizing to speculate that an ancestral form of full-length BID, similar to BOK,45, 46, 47 may have had a BAX/BAK1-like killing function. Figure 3 Speculative evolution of the BCL2 protein subfamilies. The first members were like pro-apoptotic BAX and BAK1, and had ...
Full size image In healthy cells, BAX and BAK are proposed to be inactive and do not need to be controlled by antiapoptotic BCL-2 proteins.110 Cellular stresses lead to the activation of only a fraction of the effectors BAX and BAK by the direct activators, which in turn engages a feedfo...
2 and Bax are very similar given their sequence homology with Bcl-xL. Interestingly, the structure of the Bcl-xL monomer is not consistent with the ability of Bcl-2 and Bax to form homodimers and heterodimers with each other. In Bcl-xL, the hydrophobic face of the amphipathic alpha-2 ...
The COMe-bCL6(R E2S) offers increased performance density together with excellent graphic support on a standardized Type 6 Computer-on-Module based on the COM Express basic form factor. Through the use of consistent COM Express connectors and feature implementation, the COMe-bCL6 is easily ...
Bax itself has been reported to form a homodimer (68, 160, 213), and it is thought that the Bax dimer is the lethal form of the protein. Bcl-2 disrupts the Bax dimer by displacing one of its Bax chains, forming a Bax · Bcl-2 dimer that no longer promotes apoptosis. A high Bcl...