Bafilomycin A1 BafilomycinA1 (BafA1) is amacrolideantibioticthat selectively inhibits the vacuolar type H+-ATPase (V-ATPase) and prevents the acidification of organelles containing thisenzyme(Figure 8.1). Disruption of vesicular acidification by BafA1 has been proposed to prevent the maturation of auto...
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