Bafilomycin A1 可抑制特定的酶活性。这种物质在细胞代谢调控方面有着独特的原理。它对于细胞内物质运输的过程存在抑制作用。Bafilomycin A1 能够干扰细胞内的离子平衡。其原理可能与影响某些蛋白质的功能有关。该物质在细胞自噬的调节中有特定的作用机制。 它对于细胞内的信号传导通路可能产生阻断效应。Bafilomycin A1 ...
Examines the effects of bafilomycin A[sub 1], a blocker of vacuolar hydrogen-ATPase, on rhinovirus (RV) infection in the airway epithelium. Suggestion that bafilomycin A[sub 1] may inhibit RV infection by reducing intercellular adhesion molecule (ICAM)-1 expression in the epithelial cells; Modul...
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不要忽略了lc3-2除了通过溶酶体降解以外还可以通过裂解PE重新变回LC3-1
摘要: Examines the synthesis of bafilomycin A, an enantiomer of adenosine triphosphatase inhibitor. Aldol reaction between methyl ketone and aldehyde; Macrocyclization of the seco ester precursor; Stereochemistry of the aldol.被引量: 26 年份: 2002 ...
OPMA00072 was found to produce inhibitors of the synthesis of neutral lipids in a cell-based assay using Chinese hamster ovary (CHO) cells. A new 16-membered macrolide named bafilomycin L (BFL) (1) was isolated along with the known structurally related bafilomycin C1 (BFC1) (3) from the ...
To examine the relationship between endosome acidification and receptor trafficking, transferrin receptor trafficking was characterized in Chinese hamster ovary cells in which endosome acidification was blocked by treatment with the specific inhibitor of the vacuolar H(+)-ATPase, bafilomycin A1. Elevating ...
Oligomycin和aurovertin在melan-a黑素细胞增加染色。 Bafilomycin,禁止vacuolar腺苷三磷酸酶的知道的染色改进物,为比较是包括的。 每个数据点是平均24-well组织文化板材的二口井。 简称: Oligo = oligomycin, Auro = aurovertin, Baf = bafilomycin。[translate]...
Takuya Hashimoto2,3, Mamoru Komatsu1, Makoto Nishiyama2, Tomohisa Kuzuyama2 and Haruo Ikeda1 Bafilomycins A1, C1 and B1 (setamycin) produced by Kitasatospora setae KM-6054 belong to the plecomacrolide family, which exhibit antibacterial, antifungal, antineoplastic and immunosuppressive activities. ...
The effect of bafilomycin A(1) on intracellular pH of single cells in the mouse proximal tubule 来自 ResearchGate 喜欢 0 阅读量: 7 作者:G Capasso,C Saviano,M Rizzo,NG Desanto 摘要: The connecting tubule (CNT) of superficial nephrons comes into close contact with the corresponding afferent ...