Beta-lactamase-negative strains were more susceptible to most antimicrobials than beta-lactamase-positive strains, with the exception of the cephamycins. Beta-lactamase-negative Bacteroides distasonis and Bacteroides ovatus were more resistant to beta-lactam/beta-lactamase inhibitor combinations than were ...
Promoter of β-lactamase gene (PcfxA) from Bacteroides vulgatus (Parker and Smith, 1993) PBfP1E6 phage promoterfrom B. fragilis phage genomes (Whitaker et al., 2017) PAM derived from the promoter of BT1311 (Mimee et al., 2016) PAM promoters combined with RBSs of varied strength from Bac...
IMMUNOLOGICAL PROPERTIES OF A NOVEL β-LACTAMASE PRODUCED BY BACTEROIDES FRAGILIS AKIRA,YOTSUJI,SHINZABUROU,... - 《Journal of Antibiotics》 被引量: 4发表: 1984年 Crystal structure of the wide-spectrum binuclear zinc beta-lactamase from Bacteroides fragilis. The metallo-beta-lactamase from ...
fragilis group strains (94% susceptible), good activity against other .beta.-lactamase-positive strains (.gtoreq. 85% susceptible), and excellent activity against .beta.-lactamase-negative strains (100% susceptible; MIC for 90% of strains, 0.5 .mu.g/ml). Trospectomycin was active against >...
Bacteroides is an opportunistic, anaerobic, Gram-negative bacilli. Bacteroides fragilis is the most common species involved in human disease.
Insertional activation of cepA leads to high-level beta-lactamase expression in Bacteroides... Focuses on the study that shows that insertional activation of cepA leads to high-level beta-lactamase expression in Bacteroides fragilis clinical isolates... Rogers,Marc,B.,... - 《Journal of ...
The genusBacteroidescontains Gram-negative, nonsporeforming, nonmotile, anaerobic rods generally isolated from the gastrointestinal tract (GI-tract) of humans and animals. Up until about 12 years ago the genus was quite diverse and included nearly every organism that fit this generalized description....
Risk Factors for Resistance to beta-Lactam/beta-Lactamase Inhibitors and Ertapenem in Bacteroides Bacteremia The objective of this study was to determine risk Carroll,Karen,C.,... - 《Antimicrobial Agents & Chemotherapy》 被引量: 8发表: 2015年 Bacteroides fragilis Bacteremia and Infected Aortic An...
The strains showed resistance to different penicillins (40.2-93.1%), some even in the presence of beta-lactamase inhibitors, to cephalosporins (31.0-52.1%) and to frequently used antibiotics against anaerobes, such as clindamycin (32.2%) and imipenem (10.3%). The most effective antimicrobials ...
B. fragilis is known to harbor a repertoire of β-lactamases, including the endogenous cephalosporinase cepA, the cfxA β-lactamase, and the cfiA metallo-β-lactamase [15]. Importantly, the insertion sequence (IS) element upstream of the cfiA gene is recognized as a significant genetic determin...