Class D enzymes of Gram-positive bacteria have a distinct structural architecture and employ a unique substrate-binding mode that is quite different from that of all currently known class A, C and D β-lactamases. These enzymes thus constitute a previously unknown reservoir of novel antibiotic-...
Both Gram-positive and Gram-negative bacteria initially turn purple, owing to the crystal-violet stain. In the subsequent wash steps, Gram-positive bacteria retain their purple colour; by comparison, the purple stain is removed from Gram-negative bacteria by the solvent, causing them to take up...
(1994). Induction of β-lactamase and low affinity Penicillin Binding Protein 2' synthesis in Gram- positive bacteria. Bacterial Cell Wall. Elsevier Science, New York, 505-515.Joris, B., Hardt, K. and Ghuysen, J.M. (1994). Induction of β-lactamase and low affinity penicillin binding ...
The β lactamase from 4 of the isolates hydrolized the third generation cephalosporins. Conclusion Imipenem cilastatin, amikacin, ceftazidime and sulbactam cefoperazone can be used for empirical treatment of severe gram negative bacteria infection. 展开 关键词: Antibiotics Gram negative bacteria beta ...
Various species of Gram-negative bacteria were tested for susceptibility to β-lactam antibiotics and for production of β-lactamase. The rapid cephalosporin 87/312 visual test was more sensitive than either the acidometric or the iodometric test; the iodometric test was least sensitive. Characteristic...
Virginiamycin acetyltransferase (Vat) enzymes are resistance proteins that provide protection against streptogramins2, potent antibiotics against Gram-positive bacteria that inhibit the bacterial ribosome3. Owing to the challenge of selectively modifying the chemically complex, 23-membered macrocyclic scaffold...
These bacteria are facultative anaerobes and appear as Gram-positive cocci in pairs and/or chains on a Gram stain. These bacteria can be characterized by the varying hemolytic processes such as alpha, greenish discoloration indication of partial hemolysis, beta, indicating complete hemolysis, and ...
Prevalence and Antimicrobial Susceptibility of Extended-Spectrum Beta-Lactamase-Producing Bacteria in Intensive Care Units of Sanandaj General Hospitals (K... This study focused on analyzing the spread of extended-spectrum 尾-lactamase (ESBL) enzymes among Gram-negative bacteria at intensive care units ...
(2010). The phage- related chromosomal islands of Gram-positive bacteria. Nat Rev Microbiol 8: 541–551. O'Callaghan CH, Morris A, Kirby SM, Shingler AH. (1972). Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate. Antimicrob Agents Chemother 1: 283...
None of the other cefazidime resistant gram negative bacteria tested were found to be positive for MBL production with all the positive isolates determined to be Multidrug resistant (MDR) strains. Conclusion This study demonstrated a higher rate of resistance among P. aeruginosa and Acinetobacter ...