We found three planarian homologs of yeast Atg8, and named them DjAtg8A, DjAtg8B, and DjAtg8C. In situ hybridization of DjAtg8 paralogs showed that all three genes are expressed in intestine, suggesting their conserved function in endocytosis and lysosomes. In addition, 纬-irradiation ...
Since the discovery of the autophagy-related genes (ATGs) in brewer’s yeast by Yoshinori Ohsumi in the 1990s [11], scholars have identified more than 40 ATGs in yeast by genetic screening, and approximately one-half of these genes show clear homology to ATGs in mammals. AMPK and mTOR s...
A still increasing number of reports, in particular, have revealed that mutations in the autophagy-related (ATG) genes, encoding the key players of macroautophagy, are either the cause or represent a risk factor for the development of several illnesses. The aim of this review is to provide a...
Autophagy-related genes (ATG) and their functions have been identified in numerous crop species. However, their specific tasks in potatoes (Solanum tuberosum L.), are still not well understood. This work is the first to identify and characterize the potato StATG18 subfamily gene at the whole-...
genes namedAtg(autophagy-related genes). TheAtggenes have diverse functions, including the transportation of both intracellular and extracellular cargos and coordination of intracellular communication with all kinds of signaling pathways. TheAtgsinclude approximately 20 members. During the initiation and ...
This study attempted to examine the expression of several autophagy-related genes in Parkinson's disease (PD) rat model. The male Wistar rats were divided into three groups as control, sham, and lesion. In the latter group, the PD rat model was induced by the injection of 6-hydroxydopamine...
Identification of autophagy-related genes ATG4 and ATG8 from wheat (Triticum aestivum L.) and profiling of their expression patterns responding to biotic and abiotic stresses. Plant Cell Rep 2014; 33: 1697-1710.Pei, D.; Zhang, W.; Sun, H.; Wei, X.; Yue, J.; Wang, H. Identification...
Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability. Kang Mi Ran,Kim Min Sung,Oh Ji Eun,Kim Yoo Ri,Song Sang Yong,Kim Sung Soo,Ahn Chang Hyeok,Yoo Nam Jin,Lee Sug Hyung. The Journal of pathology ...
Autophagy-related genes (ATG) and their functions have been identified in numerous crop species. However, their specific tasks in potatoes (Solanum tuberosum L.), are still not well understood. This work is the first to identify and characterize the potato StATG18 subfamily g...
The aim of this study was to explore the prognostic value of autophagy-related genes(ATGs) in patients with OSCC. RNA-seq and clinical data were downloaded from TCGA database following extrating ATGs expression profiles. Then, differentially expressed analysis was performed in R software EdgeR ...