Autophagy-related genes (ATG) and their functions have been identified in numerous crop species. However, their specific tasks in potatoes (Solanum tuberosum L.), are still not well understood. This work is the first to identify and characterize the potato StATG18 subfamily g...
Up to now 35 AuTophagy-related Genes (ATG) have been identified in the yeast, and 16 ATG genes have orthologues in human[3]. These ATG gene products function at different stages of autophagy process and can be classified into 5 major functional groups: (i) the ULK1 kinase complex, (ii)...
Autophagy-related genes (ATG) and their functions have been identified in numerous crop species. However, their specific tasks in potatoes (Solanum tuberosum L.), are still not well understood. This work is the first to identify and characterize the potato StATG18 subfamily gene at the whole-...
[7]. Autophagy related (ATG) genes are evolutionarily conserved and tightly regulate the production of autophagosomes [18], which is divided into five distinct stages: initiation, nucleation of the autophagosome, expansion and elongation of the autophagosome membrane, closure and fusion with the ...
Then the RT-PCR technique was employed to evaluate the expressions ofp62/SQSTM, autophagy-related genes(ATG)5,ATG12,ATG16L1,ATG10, as well asGAPDHandLC3. By injecting apomorphine, the striatal lesion group showed a significant contralateral rotation at fourth week as compared to the baseline. ...
related genes (the ATG genes) are conserved from yeast to mammals.They regulate the cannibalism of intracellular cytoplasm, proteins,and organelles,although we know little about autophagy-related-genes. Thus,many problems about mechanism of autophay remian unresolved and many researcher are struggling ...
several key factors regulating this intracellular degradation process have been identified. The so-called autophagy-related (ATG) genes and proteins are central to this process. However, several additional molecules contribute to the outcome of an autophagic response. Several review articles describing the...
Autophagy-related genes AMPK: Adenosine 5′-monophosphate-activated protein kinase mTOR: Mammalian target of rapamycin ULK1: Unc-51-like autophagy-activating kinase-1 RB1CC1: RB1-inducible coiled-coil 1 PI3K: Phosphoinositide 3-kinase AKT:
Till now, over 30 AuTophaGy-related (Atg) genes have been identified in yeast Saccharomyces cerevisiae, and their homologs were characterized in higher eukaryotes. These ATG proteins are hierarchically recruited to the autophagosome formation site for the boosting of the core autophagic machinery, which...
This study aimed to investigate the potential of autophagy-related genes (ATGs) as a prognostic signature for HCC and explore their relationships with immune cells and immune checkpoint molecules. A total of 483 samples were collected from the GEO databa